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Target
D(2) dopamine receptor
Ligand
BDBM50436531
Substrate
n/a
Meas. Tech.
ChEMBL_966657 (CHEMBL2399862)
Ki
170±n/a nM
Citation
 Reinart-Okugbeni, R; Vonk, A; Uustare, A; Gyulai, Z; Sipos, A; Rinken, A 1-substituted apomorphines as potent dopamine agonists. Bioorg Med Chem 21:4143-50 (2013) [PubMed]  Article
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50436531
Synonyms:
CHEMBL2397385
Type:
Small organic molecule
Emp. Form.:
C28H25NO3
Mol. Mass.:
423.503
SMILES:
CN1CCc2ccc(Cc3ccc(O)c4ccccc34)c-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r|
Structure:
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