Reaction Details 
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Polyprotein II
Ligand
BDBM50212469
Substrate
n/a
Meas. Tech.
ChEBML_28873
IC50
126000±n/a nM
Citation
TBA Bioorg Med Chem Lett 2:145-148 (1992) More Info.:
Target
Name:
Polyprotein II
Synonyms:
Avian myoblastosis virus polyprotein II
Type:
PROTEIN
Mol. Mass.:
98728.91
Organism:
Avian myeloblastosis virus
Description:
ChEMBL_331788
Residue:
893
Sequence:
IGRATVLTVALHLAIPLKWKPNHTPVWIDQWPLPEGKLVALTQLVEKELQLGHIEPSLSCWNTPVFVIRKASGSYRLLHDLRAVNAKLVPFGAVQQGAPVLSALPRGWPLMVLDLKDCFFSIPLAEQDREAFAFTLPSVNNQAPARRFQWKVLPQGMTCSPTICQLIVGQILEPLRLKHPSLRMLHYMDDLLLAASSHDGLEAAGEEVISTLERAGFTISPDKVQREPGVQYLGYKLGSTYVAPVGLVAEPRIATLWDVQKLVGSLQWLRPALGIPPRLRGPFYEQLRGSDPNEAREWNLDMKMAWREIVRLSTTAALERWDPALPLEGAVARCEQGAIGVLGQGLSTHPRPCLWLFSTQPTKAFTAWLEVLTLLITKLRASAVRTFGKEVDILLLPACFRDDLPLPEGILLALRGFAGKIRSSDTPSIFDIARPLHVSLKVRVTDHPVPGPTVFTDASSSTHKGVVVWREGPRWEIKEIADLGASVQQLEARAVAMALLLWPTTPTNVVTDSAFVAKMLLKMGQEGVPSTAAAFILEDALSQRSAMAAVLHVRSHSEVPGFFTEGNDVADSQATFQAYPLREAKDLHTALHIGPRALSKACNISMQQAREVVQTCPHCNSAPALEAGVNPRGLGPLQIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVAAQHHWATAIAVLGRPKAIKTDNGSCFTSKSTREWLARWGIAHTTGIPGNSQGQAMVERANRLLKDKIRVLAEGDGFMKRIPTSKQGELLAKAMYALNHFERGENTKTPIQKHWRPTVLTEGPPVKIRIETGEWEKGWNVLVWGRGYAAVKNRDTDKVIWVPSRKVKPDIAQKDEVTKKDEASPLFAGWRHIDKRIITLHSSFSKINLLVCFIFH
Inhibitor
Name:
BDBM50212469
Synonyms:
CHEMBL35382
Type:
Small organic molecule
Emp. Form.:
C11H15FN5O6P
Mol. Mass.:
363.2389
SMILES:
Cc1cn(C2CC(N=[N+]=[N-])C(COP(O)(=O)CF)O2)c(=O)[nH]c1=O
Structure:
