Reaction Details  Report a problem with these data
Target
Melatonin receptor type 1C
Ligand
BDBM85384
Substrate
n/a
Ki
2137.96±n/a nM
Comments
PDSP_1127
Citation
 Teh, MT; Sugden, D Comparison of the structure-activity relationships of melatonin receptor agonists and antagonists: lengthening the N-acyl side-chain has differing effects on potency on Xenopus melanophores. Naunyn Schmiedebergs Arch Pharmacol 358:522-8 (1998) [PubMed]  Article
Target
Name:
Melatonin receptor type 1C
Synonyms:
MTR1C_XENLA | Melatonin 1C | Melatonin receptor 1C | Melatonin receptor type 1C | mtnr1c
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47442.40
Organism:
Xenopus
Description:
Melatonin 1C 0 Xenopus::P49219
Residue:
420
Sequence:
MMEVNSTCLDCRTPGTIRTEQDAQDSASQGLTSALAVVLIFTIVVDVLGNILVILSVLRNKKLQNAGNLFVVSLSIADLVVAVYPYPVILIAIFQNGWTLGNIHCQISGFLMGLSVIGSVFNITAIAINRYCYICHSLRYDKLYNQRSTWCYLGLTWILTIIAIVPNFFVGSLQYDPRIFSCTFAQTVSSSYTITVVVVHFIVPLSVVTFCYLRIWVLVIQVKHRVRQDFKQKLTQTDLRNFLTMFVVFVLFAVCWAPLNFIGLAVAINPFHVAPKIPEWLFVLSYFMAYFNSCLNAVIYGVLNQNFRKEYKRILMSLLTPRLLFLDTSRGGTEGLKSKPSPAVTNNNQADMLGEARSLWLSRRNGAKMVIIIRPRKAQIAIIHQIFWPQSSWATCRQDTKITGEEDGCRELCKDGISQR
  
Inhibitor
Name:
BDBM85384
Synonyms:
Luzindole,N-pentanoyl
Type:
Small organic molecule
Emp. Form.:
C22H26N2O
Mol. Mass.:
334.4546
SMILES:
CCCCC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12
Structure:
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