Reaction Details 
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Neuropeptide FF receptor 2
Ligand
BDBM86142
Substrate
n/a
Ki
5.3±n/a nM
Comments
PDSP_3000
Citation
Engström, M; Brandt, A; Wurster, S; Savola, JM; Panula, P Prolactin releasing peptide has high affinity and efficacy at neuropeptide FF2 receptors. J Pharmacol Exp Ther 305:825-32 (2003) [PubMed] ArticleMore Info.:
Target
Name:
Neuropeptide FF receptor 2
Synonyms:
G-protein coupled receptor 74 | G-protein coupled receptor HLWAR77 | GPR74 | NPFF2 | NPFF2_HUMAN | NPFFR2 | NPGPR | Neuropeptide FF receptor 2 | Neuropeptide G-protein coupled receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
60293.78
Organism:
Homo sapiens (Human)
Description:
NPFF2 0 HUMAN::Q9Y5X5
Residue:
522
Sequence:
MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRRLGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
Inhibitor
Name:
BDBM86142
Synonyms:
1DMe-Y8Fa | CAS_132709 | NSC_132709
Type:
Small organic molecule
Emp. Form.:
C55H78N14O11
Mol. Mass.:
1111.295
SMILES:
[#6]-[#6](-[#6])-[#6]-[#6](-[#7](-[#6])-[#6](=O)-[#6](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6]-1-[#6](=O)-[#7]-[#6](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6](-[#6]-c1ccccc1)-[#6](-[#7])=O
Structure:
