Reaction Details  Report a problem with these data
Target
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Ligand
BDBM50080321
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
5.2e+4±n/a nM
Citation
 Dupouy, C; Zhang, C; Padilla, A; Pochet, S; Kaminski, PA Probing the active site of the deoxynucleotide N-hydrolase Rcl encoded by the rat gene c6orf108. J Biol Chem 285:41806-14 (2010) [PubMed]  Article
Target
Name:
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
Synonyms:
DNPH1_RAT | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) D69N | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) E93Q | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) S117A | Deoxyribonucleoside 5'-monophosphate N-glycosidase (Rcl) Y13F | Dnph1 | Rcl | c-Myc-responsive protein Rcl
Type:
Enzyme
Mol. Mass.:
17775.23
Organism:
Rattus norvegicus (Rat)
Description:
O35820
Residue:
163
Sequence:
MAASGEQAPCSVYFCGSIRGGREDQALYARIVSRLRRYGKVLTEHVADAELEPLGEEAAGGDQFIHEQDLNWLQQADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMIRGAADGSRFQVWDYAEGEVETMLDRYFEAYLPQKTASSSHPSA
  
Inhibitor
Name:
BDBM50080321
Synonyms:
ZMP | [5-(5-amino-4-carbamoyl-1H-imidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
Type:
Small organic molecule
Emp. Form.:
C9H13N4O8P
Mol. Mass.:
336.1964
SMILES:
NC(=O)c1ncn(C2OC(COP([O-])([O-])=O)C(O)C2O)c1N
Structure:
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