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Target
Serine protease 1
Ligand
BDBM98593
Substrate
n/a
Meas. Tech.
Enzyme Assay
Temperature
297.15±0 K
Ki
20±0.0 nM
Citation
 Stuerzebecher, J; Steinmetzer, T; Schweinitz, A Urokinase inhibitors, production and use thereof US Patent  US8476306 Publication Date 7/2/2013
Target
Name:
Serine protease 1
Synonyms:
PTRYI | Prss1 | RATPTRYI | TRY1_RAT | Trp1 | Try1 | Tryp1 | Trypsin
Type:
Protein
Mol. Mass.:
25951.67
Organism:
Rattus norvegicus
Description:
P00762
Residue:
246
Sequence:
MSALLILALVGAAVAFPLEDDDKIVGGYTCPEHSVPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEGDEQFINAAKIIKHPNYSSWTLNNDIMLIKLSSPVKLNARVAPVALPSACAPAGTQCLISGWGNTLSNGVNNPDLLQCVDAPVLSQADCEAAYPGEITSSMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALPDNPGVYTKVCNFVGWIQDTIAAN
  
Inhibitor
Name:
BDBM98593
Synonyms:
US8476306, 6.19 | methyl 4-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methylamino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]sulfamoylmethyl]benzoate
Type:
Small organic molecule
Emp. Form.:
C23H29N5O8S
Mol. Mass.:
535.57
SMILES:
COC(=O)c1ccc(CS(=O)(=O)N[C@H](CO)C(=O)N[C@@H](CO)C(=O)NCc2ccc(cc2)C(N)=N)cc1
Structure:
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