Reaction Details  Report a problem with these data
Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM186936
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Ki
4827±n/a nM
Comments
extracted
Citation
 Besnard, J; Hopkins, AL; Gilbert, I; Ruda, GF; Abecassis, K Morpholino compounds, uses and methods US Patent  US9079895 Publication Date 7/14/2015
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_MOUSE | 5ht1b | Htr1b
Type:
Enzyme
Mol. Mass.:
43090.29
Organism:
Mus musculus (Mouse)
Description:
P28334
Residue:
386
Sequence:
MEEQGIQCAPPPPAASQTGVPLTNLSHNCSADGYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVEYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEMLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCAG
  
Inhibitor
Name:
BDBM186936
Synonyms:
US9079895, 24s
Type:
Small organic molecule
Emp. Form.:
C22H26N2O4
Mol. Mass.:
382.4528
SMILES:
COc1cccc(OC[C@@H]2CN(CC(=O)N3CCc4ccccc34)CCO2)c1 |r|
Structure:
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