Reaction Details  Report a problem with these data
Target
Ryanodine receptor 1 [4317-4329]
Ligand
BDBM430034
Substrate
n/a
Meas. Tech.
QSS Assist FP assay
IC50
0.800±n/a nM
Citation
 Sugimoto, T; Sakamoto, T; Yamamoto, F; Kobayakawa, Y; Egashira, N; Ichikawa, K; Machida, T 5H-pyrrolo[2,3-D]pyrimidin-6(7H)-one derivative US Patent  US10538528 Publication Date 1/21/2020
Target
Name:
Ryanodine receptor 1 [4317-4329]
Synonyms:
Biotinylated Substrate Peptide | RYDR | RYR1 | RYR1_HUMAN
Type:
Peptide
Mol. Mass.:
2871.44
Organism:
n/a
Description:
P21817[4317-4329]
Residue:
24
Sequence:
ITINCLINKERVRRLRRLTAREAA
 
Inhibitor
Name:
BDBM430034
Synonyms:
US10538528, Compound 16
Type:
Small organic molecule
Emp. Form.:
C29H35FN8O2
Mol. Mass.:
546.639
SMILES:
COc1cc(c(F)cn1)-c1ccc(NCCN2CCCC2)c(n1)C1CCN(CC1)c1ncnc2NC(=O)C(C)c12
Structure:
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