| Assay Method Information | |
| | Biochemical Assay |
| Description: | Compound 1 was not initially reported as having the greatest biochemical potency compared to reports for certain other small molecule inhibitors of mIDH-1. Structurally distinct compounds (e.g., AG-120, AG-881, IDH305, IDH889, GSK321, and Bay1436032) and other certain quinolinone-based compounds were initially reported as having greater in vitro potency in biochemical assays measuring activity against certain mIDH-1 isoforms. |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |