| Assay Method Information | |
| | ChEMBL_2024838 (CHEMBL4678651) |
| Description: | Inhibition of ABCB1 in multidrug-resistant human SW620/Ad300 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 pre-incubated for 4 hrs followed by paclitaxel addition and measured after 72 hrs by MTT assay (Rvb = 4.23 +/- 0.6 uM) |
| Affinity data for this assay | |
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