Assay Method Information | |
| ChEMBL_1913768 (CHEMBL4416351) |
Description: | Inhibition of human DOT1L expressed in Escherichia coli assessed as reduction in methylated polynucleosome level using polynucleosome as substrate in presence of [3H] SAM incubated for 15 mins by scintillation counting |
Affinity data for this assay | |
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