Compile Data Set for Download or QSAR
Found 34 of affinity data for UniProtKB/TrEMBL: P09086
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM335495((2R,5S,13aR)—N-(2-chloro-4-fluorobenzyl)-8-hy...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330054((2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,5-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330049((13aS)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluorobenzy...)copy SMILEScopy InChI
Affinity DataIC50: 137nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM448201(US10689399, Compound 40)copy SMILEScopy InChI
Affinity DataIC50: 204nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM350693(US9795602, Compound 29)copy SMILEScopy InChI
Affinity DataIC50: 216nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35WTBUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330039((2R,5S,13aR)-N-(2,4-difluorobenzyl)-8-hydroxy-7,9-...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330040((2S,5R,13aS)-N-(2,4-difluorobenzyl)-8-hydroxy-7,9-...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM448200(US10689399, Compound 39)copy SMILEScopy InChI
Affinity DataIC50: 358nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM448216(US10689399, Compound 100)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330052((1R,4S,12aS)-7-hydroxy-6,8-dioxo-N-(2,4,6-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 476nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330048((2R,5S,13aR)-8-hydroxy-7,9-dioxo-N-(2,4,6-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 487nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM448198(US10689399, Compound 13)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM448213(US10689399, Compound 96)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330060((1R,3S,4R,12aR)-7-hydroxy-3-methyl-6,8-dioxo-N-(2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330041( (4R,12aS)-N-(1-(2,4-difluorophenyl)cyclopropyl)-7...)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM350694(US9795602, Compound 58)copy SMILEScopy InChI
Affinity DataIC50: 2.49E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35WTBUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM350830(US9795602, Compound 59)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35WTBUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330047((1R,4S,12aR)-7-hydroxy-6,8-dioxo-N-(2,4,6-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 2.82E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330059((1S,4R,12aR)-3,3-difluoro-7-hydroxy-6,8-dioxo-N-(2...)copy SMILEScopy InChI
Affinity DataIC50: 3.73E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330055((1R,4S,12aR)-7-hydroxy-6,8-dioxo-N—((R)-1-(2,...)copy SMILEScopy InChI
Affinity DataIC50: 3.83E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330051((1S,4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-6,8-...)copy SMILEScopy InChI
Affinity DataIC50: 4.91E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330050((1R,4S,12aR)-N-(2,4-difluorobenzyl)-7-hydroxy-6,8-...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM350834(US9795602, Compound 12)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35WTBUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330057((1S,4R,12aS)-3,3-difluoro-7-hydroxy-6,8-dioxo-N-(2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330056((1S,3R,4R,12aR)-3-fluoro-7-hydroxy-6,8-dioxo-N-(2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM350831(US9795602, Compound 31)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35WTBUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM350832(US9795602, Compound 32)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35WTBUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM350833(US9795602, Compound 39)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35WTBUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330044( (2S,5R)-N—((S)-1-(2,4-difluorophenyl)-2,2,2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM330042((2S,5R,13aS)-N—((R)-1-(2,4-difluorophenyl)eth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S185HXUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM350836(US9795602, Compound 28)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35WTBUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM350835(US9795602, Compound 25b)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K35WTBUS Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM50576849(CHEMBL4876008)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of OCT2 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP78Q8PubMed
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM50228403((R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-met...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of OCT2 (unknown origin) expressed in HEK293 cells assessed as reduction of [14C]metformin substrate uptake at 100 uM by liquid scintillat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC0574PubMed