Affinity DataIC50: 17nMAssay Description:Antagonist activity at mouse TRPV4More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 17nMAssay Description:Antagonist activity at mouse TRPV4 expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-induced current at holding potential of -40 mV by W...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at mouse TRPV4More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at mouse TRPV4 expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-induced intracellular calcium after 10 mins in pres...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of YFP-tagged mouse TRPV4 expressed in HEK293 cells assessed as reduction in calcium level by fluo-4 dye based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.25E+4nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: 370nMAssay Description:Agonist activity at mouse TRPV4More data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at mouse TRPV4More data for this Ligand-Target Pair
Affinity DataEC50: 770nMAssay Description:Agonist activity at mouse TRPV4More data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at mouse TRPV4More data for this Ligand-Target Pair
Affinity DataEC50: 2.83E+3nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: 175nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: 370nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: 450nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
