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Compile Data Set for Download or QSAR

Found 2 hits of affinity data for UniProtKB/TrEMBL: A0A3Q7SEB1   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase


(Dog)
BDBM510496
PNG
(US11077111, Compound IVa | US20230295171, Example ...)
Show SMILES Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(Cl)c2CNC(=O)c12
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 323n/an/an/an/an/an/a


TBA

Assay Description
A radiometric protein kinase assay was used for measuring the kinase activity of the Dog (Canis lupus familiaris) IRAK4, JAK1, JAK2, SYK kinases. All...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2K35XS9
More data for this
Ligand-Target Pair
Tyrosine-protein kinase


(Dog)
BDBM50204290
PNG
(CHEMBL3979920 | US11077111, Compound IIIa | US2023...)
Show SMILES Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(F)c2CNC(=O)c12 |r|
Show InChI InChI=1S/C17H21FN6O/c1-24-8-9(6-21-24)15-13-10(7-20-17(13)25)14(18)16(23-15)22-12-5-3-2-4-11(12)19/h6,8,11-12H,2-5,7,19H2,1H3,(H,20,25)(H,22,23)/t11-,12+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Similars

PDB
US Patent
n/an/a 4.62E+3n/an/an/an/an/an/a


TBA

Assay Description
A radiometric protein kinase assay was used for measuring the kinase activity of the Dog (Canis lupus familiaris) IRAK4, JAK1, JAK2, SYK kinases. All...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2K35XS9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)