The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
12639560 |
34 |
Novel N1-(benzyl)cinnamamidine derived NR2B subtype-selective NMDA receptor antagonists.![EBI](/images/logo_chembl.png) |
Merck Sharp & Dohme Research Laboratories |
18434149 |
23 |
Reactive derivatives for affinity labeling in the ifenprodil site of NMDA receptors.![EBI](/images/logo_chembl.png) |
University of Strasburg |
11909726 |
36 |
5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition.![EBI](/images/logo_chembl.png) |
Novartis Pharma |
20965739 |
66 |
Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols.![EBI](/images/logo_chembl.png) |
Institut FüR Pharmazeutische Und Medizinische Chemie Der WestfäLischen Wilhelms-UniversitäT MüNster |
20875744 |
6 |
Synthesis and biological evaluation of radio-iodinated benzimidazoles as SPECT imaging agents for NR2B subtype of NMDA receptor.![EBI](/images/logo_chembl.png) |
Hamamatsu University School of Medicine |
20361801 |
100 |
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.![EBI](/images/logo_chembl.png) |
Friedrich-Schiller-Universitat Jena |
15225705 |
19 |
Oxamides as novel NR2B selective NMDA receptor antagonists.![EBI](/images/logo_chembl.png) |
Gedeon Richter |
14552795 |
13 |
Indole-2-carboxamides as novel NR2B selective NMDA receptor antagonists.![EBI](/images/logo_chembl.png) |
Gedeon Richter |
31390523 |
56 |
Neuroactive Steroid ![EBI](/images/logo_chembl.png) |
Sage Therapeutics |
30891123 |
204 |
1![EBI](/images/logo_chembl.png) |
Janssen Research & Development |
29446949 |
82 |
Positive and Negative Allosteric Modulators of N-Methyl-d-aspartate (NMDA) Receptors: Structure-Activity Relationships and Mechanisms of Action.![EBI](/images/logo_chembl.png) |
University of Bristol |
31351393 |
17 |
A novel class of multitarget anti-Alzheimer benzohomoadamantane?chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.![EBI](/images/logo_chembl.png) |
University of Barcelona |
31319263 |
49 |
Discovery of new potent dual sigma receptor/GluN2b ligands with antioxidant property as neuroprotective agents.![EBI](/images/logo_chembl.png) |
University of Trieste |
26531150 |
15 |
Benzo[7]annulene-based GluN2B selective NMDA receptor antagonists: Surprising effect of a nitro group in 2-position.![EBI](/images/logo_chembl.png) |
University Munster |
26171651 |
19 |
A New Class of Potent N-Methyl-D-Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D-Ring Modifications.![EBI](/images/logo_chembl.png) |
Academy of Sciences of The Czech Republic V.V.I. |
21453995 |
20 |
Synthesis, evaluation and metabolic studies of radiotracers containing a 4-(4-[18F]-fluorobenzyl)piperidin-1-yl moiety for the PET imaging of NR2B NMDA receptors.![EBI](/images/logo_chembl.png) |
I2Bm |
21334205 |
30 |
Novel analogues of ketamine and phencyclidine as NMDA receptor antagonists.![EBI](/images/logo_chembl.png) |
Glaxosmithkline Medicines Research Centre |
20692832 |
6 |
Identification of a novel NR2B-selective NMDA receptor antagonist using a virtual screening approach.![EBI](/images/logo_chembl.png) |
Universit£ |
17624774 |
28 |
Design, synthesis, and biological evaluation of tricyclic heterocycle-tetraamine conjugates as potent NMDA channel blockers.![EBI](/images/logo_chembl.png) |
Chiba University |
15056006 |
69 |
NR2B-selective N-methyl-D-aspartate antagonists: synthesis and evaluation of 5-substituted benzimidazoles.![EBI](/images/logo_chembl.png) |
Merck Research Laboratories |
30103189 |
21 |
Pyridine bioisosteres of potent GluN2B subunit containing NMDA receptor antagonists with benzo[7]annulene scaffold.![EBI](/images/logo_chembl.png) |
Institut F£R Pharmazeutische Und Medizinische Chemie Der Westf£Lischen Wilhelms-Universit£T M£Nster |
28947933 |
9 |
Modulating GluN2B for the Treatment of Neurological and Psychiatric Disorders.![EBI](/images/logo_chembl.png) |
Amri |
28797770 |
13 |
Replacement of benzylic hydroxy group by vinyl or hydroxymethyl moiety at the 3-benzazepine scaffold retaining GluN2B affinity.![EBI](/images/logo_chembl.png) |
Universit£T M£Nster |