The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26961283 |
10 |
In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives.![EBI](/images/logo_chembl.png) |
Universidad Aut£Noma Del Estado De Morelos |
26191366 |
66 |
Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.![EBI](/images/logo_chembl.png) |
Indiana University School of Medicine |
25264584 |
20 |
Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition.![EBI](/images/logo_chembl.png) |
Universidad Aut£Noma Del Estado De Morelos |
25938987 |
49 |
Is RK-682 a promiscuous enzyme inhibitor? Synthesis and in vitro evaluation of protein tyrosine phosphatase inhibition of racemic RK-682 and analogues.![EBI](/images/logo_chembl.png) |
University of Campinas |
25907364 |
29 |
A potent and selective inhibitor for the UBLCP1 proteasome phosphatase.![EBI](/images/logo_chembl.png) |
Indiana University |
25003231 |
59 |
Therapeutic potential of targeting the oncogenic SHP2 phosphatase.![EBI](/images/logo_chembl.png) |
Indiana University School of Medicine |
24287560 |
61 |
Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells.![EBI](/images/logo_chembl.png) |
University of Messina |
23713581 |
75 |
A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.![EBI](/images/logo_chembl.png) |
Indiana University School of Medicine |
23305444 |
171 |
Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.![EBI](/images/logo_chembl.png) |
Indiana University School of Medicine |
21988196 |
15 |
Low molecular weight phosphotyrosine protein phosphatases as emerging targets for the design of novel therapeutic agents.![EBI](/images/logo_chembl.png) |
University of Messina |
21341673 |
106 |
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.![EBI](/images/logo_chembl.png) |
University of Southern California |
21453996 |
20 |
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: in vitro, in silico, and in vivo approaches.![EBI](/images/logo_chembl.png) |
Universidad Aut£Noma Del Estado De Morelos |
22381357 |
41 |
New 4-[(5-arylidene-2-arylimino-4-oxo-3-thiazolidinyl)methyl]benzoic acids active as protein tyrosine phosphatase inhibitors endowed with insulinomimetic effect on mouse C2C12 skeletal muscle cells.![EBI](/images/logo_chembl.png) |
University of Messina |
17543532 |
46 |
5-Arylidene-2,4-thiazolidinediones as inhibitors of protein tyrosine phosphatases.![EBI](/images/logo_chembl.png) |
Universit£ |
21669525 |
18 |
Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening.![EBI](/images/logo_chembl.png) |
Indiana University |
19889539 |
49 |
Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.![EBI](/images/logo_chembl.png) |
University of California |
20170098 |
21 |
Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).![EBI](/images/logo_chembl.png) |
Indiana University School of Medicine |
19297174 |
41 |
Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors.![EBI](/images/logo_chembl.png) |
University of Modena and R.E. |
19217304 |
44 |
5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors.![EBI](/images/logo_chembl.png) |
University of Messina |
16759857 |
59 |
Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.![EBI](/images/logo_chembl.png) |
Procter & Gamble Pharmaceuticals |
32631543 |
1 |
SAR of non-hydrolysable analogs of pyridoxal 5'-phosphate against low molecular weight protein tyrosine phosphatase isoforms.![EBI](/images/logo_chembl.png) |
Saint John'S University |
29155585 |
9 |
Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment.![EBI](/images/logo_chembl.png) |
Chinese Academy of Sciences |
29116812 |
29 |
X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors.![EBI](/images/logo_chembl.png) |
Yale University |
28017602 |
2 |
A Common Platform for Antibiotic Dereplication and Adjuvant Discovery.![BDB](/images/logo_bindingdb.png) |
Mcmaster University |