The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
24411477 |
84 |
Carbamazepine derivatives with P2X4 receptor-blocking activity. |
University of Bonn |
24246730 |
34 |
Design and synthesis of potent and selective P2X3 receptor antagonists derived from PPADS as potential pain modulators. |
Gwangju Institute of Science and Technology (Gist) |
23510563 |
9 |
Synthesis and structure-activity relationships of carboxylic acid derivatives of pyridoxal as P2X receptor antagonists. |
Gwangju Institute of Science and Technology |
23121096 |
86 |
Ion channels as therapeutic targets: a drug discovery perspective. |
Pfizer |
16250663 |
8 |
Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency. |
University of Bonn |
20045645 |
66 |
Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist. |
Roche Palo Alto |
23075067 |
98 |
N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. |
University of Bonn |
22370269 |
44 |
Discovery of P2X3 selective antagonists for the treatment of chronic pain. |
Astrazeneca |
17483457 |
58 |
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. |
Abbott Laboratories |
17676725 |
6 |
Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist. |
Institute of Science and Technology |
11831909 |
4 |
Novel antagonists acting at the P2Y(1) purinergic receptor: synthesis and conformational analysis using potentiometric and nuclear magnetic resonance titration techniques. |
Universit£ |
12213051 |
207 |
Purine and pyrimidine (P2) receptors as drug targets. |
National Institute of Diabetes |
15927468 |
3 |
Discovery and synthesis of a novel and selective drug-like P2X(1) antagonist. |
Roche Palo Alto |
32345019 |
134 |
Discovery and Structure Relationships of Salicylanilide Derivatives as Potent, Non-acidic P2X1 Receptor Antagonists. |
University of Bonn |
27427902 |
93 |
Potent Suppressive Effects of 1-Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion. |
Gwangju Institute of Science and Technology (Gist) |
30996785 |
44 |
Investigation on 2',3'- |
University of Camerino |
27426300 |
54 |
New P2X3 receptor antagonists. Part 2: Identification and SAR of quinazolinones. |
Gedeon Richter |
27423478 |
146 |
New P2X3 receptor antagonists. Part 1: Discovery and optimization of tricyclic compounds. |
Gedeon Richter |
30728111 |
81 |
Pyrrolinone derivatives as a new class of P2X3 receptor antagonists Part 2: Discovery of orally bioavailable compounds. |
Shionogi |
31990540 |
25 |
Synthesis of Novel Potent Archazolids: Pharmacology of an Emerging Class of Anticancer Drugs. |
Universit£T Bonn |
31746599 |
78 |
Discovery and Characterization of the Potent and Selective P2X4 Inhibitor |
Bayer |
26460788 |
45 |
Novel Series of Dihydropyridinone P2X7 Receptor Antagonists. |
Hoffmann-La Roche |
29548573 |
14 |
Identification of second-generation P2X3 antagonists for treatment of pain. |
Merck |
29649742 |
55 |
Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells. |
Gwangju Institute of Science and Technology (Gist) |
29805055 |
40 |
Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 1: Initial structure-activity relationship studies of a hit from a high throughput screening. |
Shionogi |
32428392 |
7 |
Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease. |
University of Georgia |
19842944 |
6 |
Inactivation of acetylcholinesterase by various fluorophores. |
The University of Montana |
28163017 |
12 |
Small-Molecule Inhibitors of the SOX18 Transcription Factor. |
The University of Queensland |
16899369 |
16 |
Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors. |
University of Florence |
19041240 |
41 |
Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment. |
Wyeth Research |
12798321 |
26 |
Nicotinyl aspartyl ketones as inhibitors of caspase-3. |
Merck Frosst Canada |
16570918 |
49 |
Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis. |
Saarland University |
10882357 |
87 |
New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis. |
Novartis Pharmaceuticals |
8295206 |
6 |
Design and synthesis of peptidomimetic inhibitors of HIV-1 protease and renin. Evidence for improved transport. |
University of Pennsylvania |