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20 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
24411477 84 Carbamazepine derivatives with P2X4 receptor-blocking activity.EBI University of Bonn
20045645 66 Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist.EBI Roche Palo Alto
23075067 98 N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists.EBI University of Bonn
17483457 58 A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.EBI Abbott Laboratories
12213051 207 Purine and pyrimidine (P2) receptors as drug targets.EBI National Institute of Diabetes
19231180 81 Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X(3)/P2X(2/3) antagonist for the treatment of pain.EBI Roche Palo Alto
19231178 61 Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain.EBI Roche Palo Alto
15927468 3 Discovery and synthesis of a novel and selective drug-like P2X(1) antagonist.EBI Roche Palo Alto
32345019 134 Discovery and Structure Relationships of Salicylanilide Derivatives as Potent, Non-acidic P2X1 Receptor Antagonists.EBI University of Bonn
27427902 93 Potent Suppressive Effects of 1-Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion.EBI Gwangju Institute of Science and Technology (Gist)
30996785 44 Investigation on 2',3'-EBI University of Camerino
30728111 81 Pyrrolinone derivatives as a new class of P2X3 receptor antagonists Part 2: Discovery of orally bioavailable compounds.EBI Shionogi
31746599 78 Discovery and Characterization of the Potent and Selective P2X4 Inhibitor EBI Bayer
26460788 45 Novel Series of Dihydropyridinone P2X7 Receptor Antagonists.EBI Hoffmann-La Roche
29649742 55 Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells.EBI Gwangju Institute of Science and Technology (Gist)
29805055 40 Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 1: Initial structure-activity relationship studies of a hit from a high throughput screening.EBI Shionogi
16899369 16 Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors.BDB University of Florence
19041240 41 Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment.BDB Wyeth Research