The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
24411477 |
84 |
Carbamazepine derivatives with P2X4 receptor-blocking activity. |
University of Bonn |
20045645 |
66 |
Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist. |
Roche Palo Alto |
23075067 |
98 |
N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. |
University of Bonn |
17483457 |
58 |
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. |
Abbott Laboratories |
12213051 |
207 |
Purine and pyrimidine (P2) receptors as drug targets. |
National Institute of Diabetes |
19231180 |
81 |
Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X(3)/P2X(2/3) antagonist for the treatment of pain. |
Roche Palo Alto |
19231178 |
61 |
Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain. |
Roche Palo Alto |
15927468 |
3 |
Discovery and synthesis of a novel and selective drug-like P2X(1) antagonist. |
Roche Palo Alto |
32345019 |
134 |
Discovery and Structure Relationships of Salicylanilide Derivatives as Potent, Non-acidic P2X1 Receptor Antagonists. |
University of Bonn |
27427902 |
93 |
Potent Suppressive Effects of 1-Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion. |
Gwangju Institute of Science and Technology (Gist) |
30996785 |
44 |
Investigation on 2',3'- |
University of Camerino |
30728111 |
81 |
Pyrrolinone derivatives as a new class of P2X3 receptor antagonists Part 2: Discovery of orally bioavailable compounds. |
Shionogi |
31746599 |
78 |
Discovery and Characterization of the Potent and Selective P2X4 Inhibitor |
Bayer |
26460788 |
45 |
Novel Series of Dihydropyridinone P2X7 Receptor Antagonists. |
Hoffmann-La Roche |
29649742 |
55 |
Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells. |
Gwangju Institute of Science and Technology (Gist) |
29805055 |
40 |
Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 1: Initial structure-activity relationship studies of a hit from a high throughput screening. |
Shionogi |
16899369 |
16 |
Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors. |
University of Florence |
19041240 |
41 |
Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment. |
Wyeth Research |