The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27326332 |
66 |
Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARa Selective Agonist. |
Bristol-Myers Squibb |
26990539 |
79 |
Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR)ß Agonist. |
Vitae Pharmaceuticals |
| 61 |
Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligands |
TBA |
| 22 |
Synthesis and receptor binding affinity of conformationally restricted retinoic acid analogues |
TBA |
| 83 |
Synthesis of highly potent RXR-specific retinoids: The use of a cyclopropyl group as a double bond isostere |
TBA |
| 54 |
Differential RXR & RAR activity of stilbene retinoid analogs bearing thiazole and imidazole carboxylic acids |
TBA |
19095448 |
24 |
Replacing alkyl sulfonamide with aromatic sulfonamide in sulfonamide-type RXR agonists favors switch towards antagonist activity. |
Okayama University Graduate School of Medicine |
16364638 |
99 |
Aza-retinoids as novel retinoid X receptor-specific agonists. |
Ligand Pharmaceuticals |
15006411 |
126 |
Design, synthesis and structure-activity relationship of novel RXR-selective modulators. |
Ligand Pharmaceuticals |
14592510 |
150 |
Design and synthesis of novel RXR-selective modulators with improved pharmacological profile. |
Ligand Pharmaceuticals |
12482435 |
75 |
Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid. |
Ligand Pharmaceuticals |
12161154 |
11 |
An improved synthesis of the C-linked glucuronide of N-(4-hydroxyphenyl)retinamide. |
The Ohio State University |
11428923 |
39 |
Enantioselective syntheses of potent retinoid X receptor ligands: differential biological activities of individual antipodes. |
Allergan |
30776227 |
38 |
Discovery of Second Generation ROR? Inhibitors Composed of an Azole Scaffold. |
Kyoto Prefectural University of Medicine |
27592633 |
13 |
Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN). |
Arizona State University |
30702885 |
256 |
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation. |
Goethe University Frankfurt |
10585206 |
45 |
Structure-activity relationship studies of novel heteroretinoids: induction of apoptosis in the HL-60 cell line by a novel isoxazole-containing heteroretinoid. |
Università |
10098670 |
24 |
Stereoselective synthesis and receptor activity of conformationally defined retinoid X receptor selective ligands. |
Allergan |
10052980 |
138 |
Synthesis of retinoid X receptor-specific ligands that are potent inducers of adipogenesis in 3T3-L1 cells. |
Ligand Pharmaceuticals |
30783504 |
87 |
Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype. |
Goethe-University Frankfurt |
9435893 |
46 |
Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers. |
University of Tokyo |
30594433 |
90 |
Discovery of potent and selective PPAR?/? dual antagonists and initial biological studies. |
Inception Sciences |
8784454 |
76 |
Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid. |
Allergan |
31531208 |
46 |
A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences. |
Goethe-University Frankfurt |
8765503 |
39 |
Identification of the first retinoid X, receptor homodimer antagonist. |
Ligand Pharmaceuticals |
8709094 |
41 |
Discovery of novel retinoic acid receptor agonists having potent antiproliferative activity in cervical cancer cells. |
Ligand Pharmaceuticals |
8308867 |
72 |
Synthesis of high specific activity [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties. |
Ligand Pharmaceuticals |
23217961 |
2 |
Structure-activity relationship study on benzoic acid part of diphenylamine-based retinoids. |
Tohoku Pharmaceutical University |
7650690 |
64 |
Conformational effects on retinoid receptor selectivity. 2. Effects of retinoid bridging group on retinoid X receptor activity and selectivity. |
Sri International |
29901398 |
29 |
Computer-Assisted Discovery of Retinoid X Receptor Modulating Natural Products and Isofunctional Mimetics. |
Swiss Federal Institute of Technology (Eth) |
28850227 |
85 |
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry. |
St. John'S University |