The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
3336036 |
83 |
New potent antagonists of leukotrienes C4 and D4. 1. Synthesis and structure-activity relationships. |
Ono Pharmaceutical |
3027332 |
18 |
Substituted (aryloxy)alkanoic acids as antagonists of slow-reacting substance of anaphylaxis. |
TBA |
3016267 |
46 |
Synthesis and structure-activity relationship studies of a series of 5-aryl-4,6-dithianonanedioic acids and related compounds: a novel class of leukotriene antagonists. |
TBA |
9873435 |
10 |
Development of new chromanol antagonists of leukotriene D4. |
Pfizer |
26985325 |
62 |
Discovery of 3-Substituted 1H-Indole-2-carboxylic Acid Derivatives as a Novel Class of CysLT1 Selective Antagonists. |
Shanghai Institute of Materia Medica |
26200813 |
90 |
Discovery of Gemilukast (ONO-6950), a Dual CysLT1 and CysLT2 Antagonist As a Therapeutic Agent for Asthma. |
Setsunan University |
25800431 |
30 |
Discovery of a potent, orally available dual CysLT1 and CysLT2 antagonist with dicarboxylic acid. |
Ono Pharmaceutical |
25408836 |
44 |
Discovery of Highly Potent Dual CysLT1 and CysLT2 Antagonist. |
Ono Pharmaceutical |
3033245 |
28 |
Leukotriene receptor antagonists. 2. The [[(tetrazol-5-ylaryl)oxy]methyl]acetophenone derivatives. |
TBA |
1331447 |
32 |
Development of a novel series of styrylquinoline compounds as high-affinity leukotriene D4 receptor antagonists: synthetic and structure-activity studies leading to the discovery of (+-)-3-[[[3-[2-(7-chloro-2-quinolinyl)-(E)-ethenyl]phenyl][[3- (dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic |
Merck Frosst Centre For Therapeutic Research |
9871597 |
65 |
A series of non-quinoline cysLT1 receptor antagonists: SAR study on pyridyl analogs of Singulair. |
Merck Frosst Center For Therapeutic Research |
9871521 |
32 |
Synthesis and SAR of a novel, potent and structurally simple LTD4 antagonist of the quinoline class. |
Novartis Pharma |
30613325 |
88 |
Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia. |
Merck |
23455026 |
2 |
Structure-based drug design using GPCR homology modeling: toward the discovery of novel selective CysLT2 antagonists. |
Zhejiang University |
9089329 |
48 |
Synthesis and structure-activity relationships of carboxylated chalcones: a novel series of CysLT1 (LTD4) receptor antagonists. |
Vrije Universiteit |
2547071 |
27 |
3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonists. |
Roche Research Center |
2342072 |
46 |
Evolution of a series of peptidoleukotriene antagonists: synthesis and structure/activity relationships of 1,3,5-substituted indoles and indazoles. |
Ici Pharmaceuticals Group |
2170649 |
37 |
The development of a novel series of (quinolin-2-ylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 3. Structural variation of the acidic side chain to give antagonists of enhanced potency. |
Rorer Central Research |
2157009 |
49 |
Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 1. Initial structure-activity relationships. |
Rorer Central Research |