The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27997879 |
15 |
Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase. |
Harvard Medical School |
21726077 |
51 |
The lipogenesis pathway as a cancer target. |
Wayne State University |
1479587 |
4 |
ATP-citrate lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-beta-lactam containing analogues of citric acid as potential tight-binding inhibitors. |
Smithkline Beecham Pharmaceuticals |
9733484 |
39 |
ATP-Citrate lyase as a target for hypolipidemic intervention. 2. Synthesis and evaluation of (3R,5S)-omega-substituted-3-carboxy-3, 5-dihydroxyalkanoic acids and their gamma-lactone prodrugs as inhibitors of the enzyme in vitro and in vivo. |
Smithkline Beecham Pharmaceuticals |
8784456 |
55 |
ATP-citrate lyase as a target for hypolipidemic intervention. Design and synthesis of 2-substituted butanedioic acids as novel, potent inhibitors of the enzyme. |
Smithkline Beecham Pharmaceuticals |
7853346 |
13 |
Synthesis of novel thiol-containing citric acid analogues. Kinetic evaluation of these and other potential active-site-directed and mechanism-based inhibitors of ATP citrate lyase. |
Smithkline Beecham Pharmaceuticals |
30195238 |
26 |
ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism. |
University of Pisa |
2788743 |
6 |
Synthesis and hypolipidemic and antidiabetogenic activities of beta,beta,beta',beta'-tetrasubstituted, long-chain dioic acids. |
Hebrew University |