22 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
25614116	13	Discovery of phenoxybutanoic acid derivatives as potent endothelin antagonists with antihypertensive activity.	Southeast University
9857090	158	Biphenylsulfonamide endothelin antagonists: structure-activity relationships of a series of mono- and disubstituted analogues and pharmacology of the orally active endothelin antagonist 2'-amino-N- (3,4-dimethyl-5-isoxazolyl)-4'-(2-methylpropyl)[1, 1'-biphenyl]-2-sulfonamide (BMS-187308).	Bristol-Myers Squibb Pharmaceutical Research Institute
9667964	38	Selective endothelin A receptor antagonists. 3. Discovery and structure-activity relationships of a series of 4-phenoxybutanoic acid derivatives.	Rh£Ne-Poulenc Rorer
9216842	28	Design of a potent combined pseudopeptide endothelin-A/endothelin-B receptor antagonist, Ac-DBhg16-Leu-Asp-Ile-[NMe]Ile-Trp21 (PD 156252): examination of its pharmacokinetic and spectral properties.	Warner-Lambert
8410970	106	Structure-activity relationships of C-terminal endothelin hexapeptide antagonists.	Warner-Lambert
1315867	31	Endothelin: a new challenge.	Warner-Lambert
1324321	20	Design of a functional hexapeptide antagonist of endothelin.	Warner-Lambert
	28	Structure-activity and biophysical studies of the C-terminal hexapeptide of endothelin	TBA
	21	Design and synthesis of nonpeptidal endothelin receptor antagonists based on the structure of a cyclic pentapeptide	TBA
	32	Quantitative structure-activity relationships study of endothelin-1 analogs	TBA
	25	Structure-activity relationships in a series of monocyclic endothelin analogues	TBA
	28	Design of C-terminal peptide antagonists of endothelin: structure-activity relationships of ET-[16–21, D-His16]	TBA
	5	CGS 27830, a potent nonpeptide endothelin receptor antagonist	TBA
11738578	26	Modifications and structure-activity relationships at the 2-position of 4-sulfonamidopyrimidine derivatives as potent endothelin antagonists.	Tanabe Seiyaku
11086733	56	Potent nonpeptide endothelin antagonists: synthesis and structure-activity relationships of pyrazole-5-carboxylic acids.	Hoechst Marion Roussel
10890162	52	Nonpeptide endothelin antagonists: from lower affinity pyrazol-5-ols to higher affinity pyrazole-5-carboxylic acids.	Hoechst Marion Roussel
27321813	286	From bosentan (Tracleer®) to macitentan (Opsumit®): The medicinal chemistry perspective.	Actelion Pharmaceuticals
7731010	56	Discovery of a novel series of orally active non-peptide endothelin-A (ETA) receptor-selective antagonists.	Warner-Lambert
7636842	155	Structure-activity relationships of the potent combined endothelin-A/endothelin-B receptor antagonist Ac-DDip16-Leu-Asp-Ile-Ile-Trp21: development of endothelin-B receptor selective antagonists.	Warner-Lambert