40 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
25333641	11	Recent advances in the development of acetyl-CoA carboxylase (ACC) inhibitors for the treatment of metabolic disease.	Amgen
25423286	26	Decreasing the rate of metabolic ketone reduction in the discovery of a clinical acetyl-CoA carboxylase inhibitor for the treatment of diabetes.	Pfizer
24294923	65	Piperazine oxadiazole inhibitors of acetyl-CoA carboxylase.	Amgen
23981033	44	Spirolactam-based acetyl-CoA carboxylase inhibitors: toward improved metabolic stability of a chromanone lead structure.	Pfizer
24900556	8	Treatment of Obesity and Related Disorders with Acetyl-CoA Carboxylase Inhibitors.	Therachem Research Medilab (India)
21726077	51	The lipogenesis pathway as a cancer target.	Wayne State University
22677317	23	Symmetrical approach of spiro-pyrazolidinediones as acetyl-CoA carboxylase inhibitors.	Takeda Pharmaceutical
22560583	48	Design, synthesis, and structure-activity relationships of novel spiro-piperidines as acetyl-CoA carboxylase inhibitors.	Takeda Pharmaceutical
21324704	4	Discovery of novel (4-piperidinyl)-piperazines as potent and orally active acetyl-CoA carboxylase 1/2 non-selective inhibitors: F-Boc and triF-Boc groups are acid-stable bioisosteres for the Boc group.	Taisho Pharmaceutical
16789734	42	Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors.	Abbott Laboratories
21944854	40	Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors.	Takeda Pharmaceutical
21515056	61	Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats.	Astrazeneca Research and Development
21082864	87	Identification and synthesis of novel inhibitors of acetyl-CoA carboxylase with in vitro and in vivo efficacy on fat oxidation.	Sanofi-Aventis Deutschland
19853443	6	(4-Piperidinyl)-piperazine: a new platform for acetyl-CoA carboxylase inhibitors.	Taisho Pharmaceutical
19740659	82	Potent biphenyl- and 3-phenyl pyridine-based inhibitors of acetyl-CoA carboxylase.	Bristol-Myers Squibb Research and Development
17383874	15	2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors.	Bristol-Myers Squibb Pharmaceutical Research Institute
17298049	28	N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy derivatives as acetyl-coA carboxylase inhibitors--improvement of cardiovascular and neurological liabilities via structural modifications.	Abbott Laboratories
17267221	56	Phenoxy thiazole derivatives as potent and selective acetyl-CoA carboxylase 2 inhibitors: Modulation of isozyme selectivity by incorporation of phenyl ring substituents.	Abbott Laboratories
17234407	60	The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: polar region modifications.	Abbott Laboratories
16973360	82	Structure-activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity.	Abbott Laboratories
31672259	13	The identification and pharmacological evaluation of potent, selective and orally available ACC1 inhibitor.	Takeda Pharmaceutical
31930920	69	The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease.	Terns Pharmaceuticals
30879862	15	Design and synthesis of a novel 1H-pyrrolo[3,2-b]pyridine-3-carboxamide derivative as an orally available ACC1 inhibitor.	Takeda Pharmaceutical
20537533	35	Design and synthesis of disubstituted (4-piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase inhibitors.	Taisho Pharmaceutical
30049586	42	Design, synthesis and biological evaluation of novel spiro-pentacylamides as acetyl-CoA carboxylase inhibitors.	China Pharmaceutical University
29903660	154	Discovery of a novel olefin derivative as a highly potent and selective acetyl-CoA carboxylase 2 inhibitor with in vivo efficacy.	Shionogi
29232514	49	Discovery of Novel Selective Acetyl-CoA Carboxylase (ACC) 1 Inhibitors.	Takeda Pharmaceutical