33 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28324649	99	Sulfonamides as Selective Na	Amgen
28287723	73	Sulfonamides as Selective Na	Amgen
27994738	50	Sulfonamides as Selective Na	Amgen
27038498	33	Discovery of triazolopyridinone GS-462808, a late sodium current inhibitor (Late INai) of the cardiac Nav1.5 channel with improved efficacy and potency relative to ranolazine.	Gilead Sciences
26985315	49	Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models.	Xenon Pharmaceuticals
26358159	114	Discovery of (phenoxy-2-hydroxypropyl)piperidines as a novel class of voltage-gated sodium channel 1.7 inhibitors.	Daiichi Sankyo
25927480	36	Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications.	Merck Research Laboratories
26101568	51	Discovery and Optimization of Selective Nav1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain.	Pfizer
24601592	48	Imidazol-1-ylethylindazole voltage-gated sodium channel ligands are neuroprotective during optic neuritis in a mouse model of multiple sclerosis.	University College London
23121096	86	Ion channels as therapeutic targets: a drug discovery perspective.	Pfizer
32392056	108	Discovery of DS-1971a, a Potent, Selective Na	Daiichi Sankyo
27441383	117	Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors.	Amgen
30943032	31	Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Na	Genentech
30538065	48	The discovery and optimization of benzimidazoles as selective Na	Pfizer
31012583	128	Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform Na	Siteone Therapeutics
29737846	70	Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa	Xenon Pharmaceuticals
29029933	45	Highly potent and selective Na	Pfizer
28682065	133	Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of Na	Icagen
26833890	18	Synthesis, Biological Evaluation, and Molecular Docking of 8-imino-2-oxo-2H,8H-pyrano[2,3-f]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease.	Yogi Vemana University
26469307	7	Phosphorylation of Capsaicinoid Derivatives Provides Highly Potent and Selective Inhibitors of the Transcription Factor STAT5b.	University of Leipzig
7932531	55	Inhibitors of HIV-1 proteinase containing 2-heterosubstituted 4-amino-3-hydroxy-5-phenylpentanoic acid: synthesis, enzyme inhibition, and antiviral activity.	Sandoz Forschungsinstitut Ges.M.B.H.