46 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28230981	37	High-Potency Phenylquinoxalinone Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activators.	University of California
28099811	23	Nanomolar-Potency Aminophenyl-1,3,5-triazine Activators of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel for Prosecretory Therapy of Dry Eye Diseases.	University of California
26041577	13	Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.	Istituto Giannina Gaslini
25019478	13	Flavones: an important scaffold for medicinal chemistry.	Punjabi University
25452003	4	¿F508-CFTR correctors: synthesis and evaluation of thiazole-tethered imidazolones, oxazoles, oxadiazoles, and thiadiazoles.	Wuhan University of Science and Technology
25441013	49	Discovery of N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (VX-770, ivacaftor), a potent and orally bioavailable CFTR potentiator.	Vertex Pharmaceuticals
25384240	4	Discovery heralds new approach to the treatment of cystic fibrosis.	Jl3Pharma
24992073	2	A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo.	Universit£
23814642	1	ABSOLUTE CONFIGURATION AND BIOLOGICAL PROPERTIES OF ENANTIOMERS OF CFTR INHIBITOR BPO-27.	University of California
18077363	314	A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.	University of Oxford
21707078	31	Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease.	University of California
21397997	5	An expeditious access to 5-pyrimidinol derivatives from cyclic methylglyoxal diadducts, formation of argpyrimidines under physiological conditions and discovery of new CFTR inhibitors.	University Joseph Fourier-Grenoble 1/Cnrs
19785436	29	Nanomolar potency pyrimido-pyrrolo-quinoxalinedione CFTR inhibitor reduces cyst size in a polycystic kidney disease model.	University of California
18691893	43	Thiazolidinone CFTR inhibitors with improved water solubility identified by structure-activity analysis.	University of California
18180157	10	Rational design of the first small-molecule antagonists of NHERF1/EBP50 PDZ domains.	St. Jude Children'S Research Hospital
15808474	43	Discovery of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid diamides that increase CFTR mediated chloride transport.	Genzyme
14761197	16	Synthesis, SAR, crystal structure, and biological evaluation of benzoquinoliziniums as activators of wild-type and mutant cystic fibrosis transmembrane conductance regulator channels.	Université
27563392	9	Targeting the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein for the Treatment of Cystic Fibrosis.	Therachem Research Medilab (India)
31326599	21	An overview on chemical structures as ?F508-CFTR correctors.	University of Palermo
31401008	34	Synthesis and biological activity of structurally diverse phthalazine derivatives: A systematic review.	Y. B. Chavan College of Pharmacy
31749908	25	Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis.	Abbvie
26561003	25	Novel Hits in the Correction of ?F508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein: Synthesis, Pharmacological, and ADME Evaluation of Tetrahydropyrido[4,3-d]pyrimidines for the Potential Treatment of Cystic Fibrosis.	Siena Biotech
25061695	23	Constrained bithiazoles: small molecule correctors of defective ?F508-CFTR protein trafficking.	University of California
22841006	5	Click-based synthesis of triazolobithiazole ?F508-CFTR correctors for cystic fibrosis.	University of California Davis
22214395	14	Structure-activity relationships of cyanoquinolines with corrector-potentiator activity in ?F508 cystic fibrosis transmembrane conductance regulator protein.	University of California Davis
22281185	3	Fluorinated ?F508-CFTR correctors and potentiators for PET imaging.	University of California Davis
20373765	10	Pyrazolylthiazole as DeltaF508-cystic fibrosis transmembrane conductance regulator correctors with improved hydrophilicity compared to bithiazoles.	University of California Davis
18394886	9	4'-Methyl-4,5'-bithiazole-based correctors of defective delta F508-CFTR cellular processing.	University of California
30078607	1	Asperidines A-C, pyrrolidine and piperidine derivatives from the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178.	Prince of Songkla University
30034584	18	Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein.	Usona Institute
29272749	126	Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.	University of Genoa
2005579	23	N-[3H]methylscopolamine labeling of non-M1, non-M2 muscarinic receptor binding sites in rat brain.	University of California
17157021	47	Acyclic, orally bioavailable ketone-based cathepsin K inhibitors.	Gsk
17941625	50	Novel aminophenyl benzamide-type histone deacetylase inhibitors with enhanced potency and selectivity.	Methylgene
17552508	128	Design and Synthesis of Classical and Nonclassical 6-Arylthio-2,4-diamino-5-ethylpyrrolo[2,3-d]pyrimidines as Antifolates.	Duquesne University
16963264	22	Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties.	Bristol-Myers Squibb Pharmaceutical Research Institute
2002465	14	L-687,908, a potent hydroxyethylene-containing HIV protease inhibitor.	Merck Research Laboratories