The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 25166285 |
17 |
Structure-guided design and optimization of small molecules targeting the protein-protein interaction between the von Hippel-Lindau (VHL) E3 ubiquitin ligase and the hypoxia inducible factor (HIF) alpha subunit with in vitro nanomolar affinities. |
University of Dundee |
| 24751445 |
15 |
Hot spot-based design of small-molecule inhibitors for protein-protein interactions. |
University of Utah |
| 23977883 |
54 |
Inhibition of hypoxia-inducible factor prolyl hydroxylase domain oxygen sensors: tricking the body into mounting orchestrated survival and repair responses. |
Janssen Research and Development |
| 24436777 |
8 |
Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? |
University of Cambridge |
| 32142281 |
24 |
Medicinal Chemistry of Inhibiting RING-Type E3 Ubiquitin Ligases. |
Genentech |
| 30682255 |
14 |
Small-Molecule Modulators of the Hypoxia-Inducible Factor Pathway: Development and Therapeutic Applications. |
China Pharmaceutical University |
| 31035238 |
3 |
Small molecule PROTACs in targeted therapy: An emerging strategy to induce protein degradation. |
Shaoxing University |
| 28692295 |
25 |
Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1. |
Arvinas |
| 29144739 |
1 |
Protac-Induced Protein Degradation in Drug Discovery: Breaking the Rules or Just Making New Ones? |
Benevolentbio |
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