Affinity Data by PubMed id=24436777

PubMed code 24436777

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM50446135 (CHEMBL3108879) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	2.40E+5	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis				ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM50446139 (CHEMBL3108882 \| US10730870, Example 135 \| US115120...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis				ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM50446134 (CHEMBL3108877) Show SMILES CNC(=O)[C@@H]1C[C@@H](O)CN1C(C)=O \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	4.90E+6	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis				ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM50446133 (CHEMBL3108875) Show SMILES CC(=O)NCc1ccc(cc1)-c1scnc1C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.70E+6	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis				ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM50446132 (CHEMBL3108874) Show SMILES CC(C)NC(=O)Cc1cc(C)no1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.30E+6	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis				ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM50446136 (CHEMBL3108878) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis				ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM50446138 (CHEMBL3108881) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis				ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human))	BDBM50446137 (CHEMBL3108880) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a
University of Cambridge Curated by ChEMBL					Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis				ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1
University of Cambridge Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%