| Reaction Details |
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 | Report a problem with these data |
| Target | von Hippel-Lindau disease tumor suppressor |
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| Ligand | BDBM50446138 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1288131 (CHEMBL3110591) |
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| Kd | 5500±n/a nM |
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| Citation |  Dias, DM; Van Molle, I; Baud, MG; Galdeano, C; Geraldes, CF; Ciulli, A Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? ACS Med Chem Lett5:23-28 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| von Hippel-Lindau disease tumor suppressor |
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| Name: | von Hippel-Lindau disease tumor suppressor |
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| Synonyms: | Protein G7 | VHL | VHL_HUMAN | Von Hippel-Lindau disease tumor suppressor | Von Hippel-Lindau disease tumor suppressor protein (VBC) | pVHL |
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| Type: | Protein |
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| Mol. Mass.: | 24136.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P40337 |
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| Residue: | 213 |
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| Sequence: | MPRRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAGRPR
PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFR
DAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDI
VRSLYEDLEDHPNVQKDLERLTQERIAHQRMGD
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| BDBM50446138 |
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| n/a |
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| Name | BDBM50446138 |
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| Synonyms: | CHEMBL3108881 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22N4O5 |
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| Mol. Mass. | 410.4232 |
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| SMILES | Cc1cc(CC(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2cnco2)on1 |r| |
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| Structure | 
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