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16 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
19746963 43 Design, synthesis, protein-ligand X-ray structure, and biological evaluation of a series of novel macrocyclic human immunodeficiency virus-1 protease inhibitors to combat drug resistance.BDB Purdue University
19473017 12 Design of HIV-1 protease inhibitors with pyrrolidinones and oxazolidinones as novel P1'-ligands to enhance backbone-binding interactions with protease: synthesis, biological evaluation, and protein-ligand X-ray studies.BDB Purdue University
18783203 15 Flexible cyclic ethers/polyethers as novel P2-ligands for HIV-1 protease inhibitors: design, synthesis, biological evaluation, and protein-ligand X-ray studies.BDB Purdue University
10387041 7 Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.BDB University of Queensland
16913714 4 Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance.BDB Purdue University
16904316 16 New, potent P1/P2-morpholinone-based HIV-protease inhibitors.BDB Glaxosmithkline
16480871 12 Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the P2'-ligands.BDB Purdue University
9871583 7 Potent HIV protease inhibitors incorporating high-affinity P2-ligands and (R)-(hydroxyethylamino)sulfonamide isostere.BDB University of Illinois At Chicago
15887965 10 Structure-based design: synthesis and biological evaluation of a series of novel cycloamide-derived HIV-1 protease inhibitors.BDB University of Illinois At Chicago
12113826 23 Novel cyclourethane-derived HIV protease inhibitors: a ring-closing olefin metathesis based strategy.BDB University of Illinois At Chicago
12419377 5 Novel spirocyclic pyrrolidones as P2/P1 mimetics in potent inhibitors of HIV-1 protease.BDB Glaxosmithkline
10866371 12 Novel inhibitors of HIV protease: design, synthesis and biological evaluation of picomolar inhibitors containing cyclic P1/P2 scaffolds.BDB Glaxosmithkline
15482949 17 Discovery of potent pyrrolidone-based HIV-1 protease inhibitors with enhanced drug-like properties.BDB Glaxosmithkline
15482948 7 Potent inhibitors of the HIV-1 protease incorporating cyclic urea P1-P2 scaffold.BDB Glaxosmithkline
15582415 17 Optimization of pyrrolidinone based HIV protease inhibitors.BDB Glaxosmithkline
15975788 23 Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors.BDB Glaxosmithkline