The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
19746963 |
43 |
Design, synthesis, protein-ligand X-ray structure, and biological evaluation of a series of novel macrocyclic human immunodeficiency virus-1 protease inhibitors to combat drug resistance. |
Purdue University |
19473017 |
12 |
Design of HIV-1 protease inhibitors with pyrrolidinones and oxazolidinones as novel P1'-ligands to enhance backbone-binding interactions with protease: synthesis, biological evaluation, and protein-ligand X-ray studies. |
Purdue University |
18783203 |
15 |
Flexible cyclic ethers/polyethers as novel P2-ligands for HIV-1 protease inhibitors: design, synthesis, biological evaluation, and protein-ligand X-ray studies. |
Purdue University |
10387041 |
7 |
Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. |
University of Queensland |
16913714 |
4 |
Structure-Based Design of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance. |
Purdue University |
16904316 |
16 |
New, potent P1/P2-morpholinone-based HIV-protease inhibitors. |
Glaxosmithkline |
16480871 |
12 |
Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the P2'-ligands. |
Purdue University |
9871583 |
7 |
Potent HIV protease inhibitors incorporating high-affinity P2-ligands and (R)-(hydroxyethylamino)sulfonamide isostere. |
University of Illinois At Chicago |
15887965 |
10 |
Structure-based design: synthesis and biological evaluation of a series of novel cycloamide-derived HIV-1 protease inhibitors. |
University of Illinois At Chicago |
12113826 |
23 |
Novel cyclourethane-derived HIV protease inhibitors: a ring-closing olefin metathesis based strategy. |
University of Illinois At Chicago |
12419377 |
5 |
Novel spirocyclic pyrrolidones as P2/P1 mimetics in potent inhibitors of HIV-1 protease. |
Glaxosmithkline |
10866371 |
12 |
Novel inhibitors of HIV protease: design, synthesis and biological evaluation of picomolar inhibitors containing cyclic P1/P2 scaffolds. |
Glaxosmithkline |
15482949 |
17 |
Discovery of potent pyrrolidone-based HIV-1 protease inhibitors with enhanced drug-like properties. |
Glaxosmithkline |
15482948 |
7 |
Potent inhibitors of the HIV-1 protease incorporating cyclic urea P1-P2 scaffold. |
Glaxosmithkline |
15582415 |
17 |
Optimization of pyrrolidinone based HIV protease inhibitors. |
Glaxosmithkline |
15975788 |
23 |
Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors. |
Glaxosmithkline |