Affinity Data by PubMed id=15482948

PubMed code 15482948

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A] (Human immunodeficiency virus type 1)	BDBM9204 ((2R,4S)-2-benzyl-5-[(5S)-5-benzyl-3-[(3-fluorophen...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.20	-48.5	n/a	n/a	n/a	n/a	n/a	6.4	25
GlaxoSmithKline					Assay Description The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...				Bioorg Med Chem Lett 14: 5685-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.038 BindingDB Entry DOI: 10.7270/Q25Q4T9W
GlaxoSmithKline					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A] (Human immunodeficiency virus type 1)	BDBM9205 ((2R,4S)-2-benzyl-5-[(5S)-5-benzyl-3-[(4-methoxyphe...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.60	-47.1	n/a	n/a	n/a	n/a	n/a	6.4	25
GlaxoSmithKline					Assay Description The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...				Bioorg Med Chem Lett 14: 5685-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.038 BindingDB Entry DOI: 10.7270/Q25Q4T9W
GlaxoSmithKline					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A] (Human immunodeficiency virus type 1)	BDBM9199 ((2R,4S)-2-benzyl-5-[(5S)-5-benzyl-2-oxo-3-(pyridin...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	18	-44.2	n/a	n/a	n/a	n/a	n/a	6.4	25
GlaxoSmithKline					Assay Description The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...				Bioorg Med Chem Lett 14: 5685-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.038 BindingDB Entry DOI: 10.7270/Q25Q4T9W
GlaxoSmithKline					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A] (Human immunodeficiency virus type 1)	BDBM9200 ((2R,4S)-2-benzyl-5-[(5S)-5-benzyl-2-oxo-3-(pyridin...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	41	-42.2	n/a	n/a	n/a	n/a	n/a	6.4	25
GlaxoSmithKline					Assay Description The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...				Bioorg Med Chem Lett 14: 5685-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.038 BindingDB Entry DOI: 10.7270/Q25Q4T9W
GlaxoSmithKline					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A] (Human immunodeficiency virus type 1)	BDBM9202 ((2R,4S)-2-benzyl-5-[(5S)-5-benzyl-2-oxo-3-[(3,4,5-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	100	-40.0	n/a	n/a	n/a	n/a	n/a	6.4	25
GlaxoSmithKline					Assay Description The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...				Bioorg Med Chem Lett 14: 5685-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.038 BindingDB Entry DOI: 10.7270/Q25Q4T9W
GlaxoSmithKline					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A] (Human immunodeficiency virus type 1)	BDBM9201 ((2R,4S)-2-benzyl-5-[(5S)-5-benzyl-2-oxo-3-(pyridin...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	190	-38.4	n/a	n/a	n/a	n/a	n/a	6.4	25
GlaxoSmithKline					Assay Description The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...				Bioorg Med Chem Lett 14: 5685-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.038 BindingDB Entry DOI: 10.7270/Q25Q4T9W
GlaxoSmithKline					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A] (Human immunodeficiency virus type 1)	BDBM9203 ((2R,4S)-2-benzyl-5-[(5S)-5-benzyl-3-[(4-methanesul...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	300	-37.2	n/a	n/a	n/a	n/a	n/a	6.4	25
GlaxoSmithKline					Assay Description The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...				Bioorg Med Chem Lett 14: 5685-7 (2004) Article DOI: 10.1016/j.bmcl.2004.08.038 BindingDB Entry DOI: 10.7270/Q25Q4T9W
GlaxoSmithKline					More data for this Ligand-Target Pair

* indicates data uncertainty>20%