41 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
24411477	84	Carbamazepine derivatives with P2X4 receptor-blocking activity.	University of Bonn
24246730	34	Design and synthesis of potent and selective P2X3 receptor antagonists derived from PPADS as potential pain modulators.	Gwangju Institute of Science and Technology (Gist)
23510563	9	Synthesis and structure-activity relationships of carboxylic acid derivatives of pyridoxal as P2X receptor antagonists.	Gwangju Institute of Science and Technology
23121096	86	Ion channels as therapeutic targets: a drug discovery perspective.	Pfizer
16250663	8	Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency.	University of Bonn
20045645	66	Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist.	Roche Palo Alto
23075067	98	N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists.	University of Bonn
22370269	44	Discovery of P2X3 selective antagonists for the treatment of chronic pain.	Astrazeneca
17483457	58	A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.	Abbott Laboratories
17676725	6	Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist.	Institute of Science and Technology
11831909	4	Novel antagonists acting at the P2Y(1) purinergic receptor: synthesis and conformational analysis using potentiometric and nuclear magnetic resonance titration techniques.	Universit£
12213051	207	Purine and pyrimidine (P2) receptors as drug targets.	National Institute of Diabetes
15927468	3	Discovery and synthesis of a novel and selective drug-like P2X(1) antagonist.	Roche Palo Alto
32345019	134	Discovery and Structure Relationships of Salicylanilide Derivatives as Potent, Non-acidic P2X1 Receptor Antagonists.	University of Bonn
27427902	93	Potent Suppressive Effects of 1-Piperidinylimidazole Based Novel P2X7 Receptor Antagonists on Cancer Cell Migration and Invasion.	Gwangju Institute of Science and Technology (Gist)
30996785	44	Investigation on 2',3'-	University of Camerino
27426300	54	New P2X3 receptor antagonists. Part 2: Identification and SAR of quinazolinones.	Gedeon Richter
27423478	146	New P2X3 receptor antagonists. Part 1: Discovery and optimization of tricyclic compounds.	Gedeon Richter
30728111	81	Pyrrolinone derivatives as a new class of P2X3 receptor antagonists Part 2: Discovery of orally bioavailable compounds.	Shionogi
31990540	25	Synthesis of Novel Potent Archazolids: Pharmacology of an Emerging Class of Anticancer Drugs.	Universit£T Bonn
31746599	78	Discovery and Characterization of the Potent and Selective P2X4 Inhibitor	Bayer
26460788	45	Novel Series of Dihydropyridinone P2X7 Receptor Antagonists.	Hoffmann-La Roche
29548573	14	Identification of second-generation P2X3 antagonists for treatment of pain.	Merck
29649742	55	Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells.	Gwangju Institute of Science and Technology (Gist)
29805055	40	Pyrrolinone derivatives as a new class of P2X3 receptor antagonists. Part 1: Initial structure-activity relationship studies of a hit from a high throughput screening.	Shionogi
32428392	7	Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease.	University of Georgia
19842944	6	Inactivation of acetylcholinesterase by various fluorophores.	The University of Montana
28163017	12	Small-Molecule Inhibitors of the SOX18 Transcription Factor.	The University of Queensland
16899369	16	Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors.	University of Florence
19041240	41	Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment.	Wyeth Research
12798321	26	Nicotinyl aspartyl ketones as inhibitors of caspase-3.	Merck Frosst Canada
16570918	49	Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis.	Saarland University
10882357	87	New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis.	Novartis Pharmaceuticals
8295206	6	Design and synthesis of peptidomimetic inhibitors of HIV-1 protease and renin. Evidence for improved transport.	University of Pennsylvania