The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
16644215 |
52 |
Design and synthesis of selective keto-1,2,4-oxadiazole-based tryptase inhibitors. |
Celera Genomics |
16554154 |
9 |
Development of activity-based probes for trypsin-family serine proteases. |
Celera Genomics |
19715320 |
87 |
Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation. |
University of Florida |
12930148 |
41 |
Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone. |
Johnson & Johnson Pharmaceutical Research & Development |
16725321 |
13 |
Novel, potent, selective, and orally bioavailable human betaII-tryptase inhibitors. |
Celera Genomics |
15911249 |
29 |
Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptase. |
Aventis Pharmaceuticals |
15745817 |
14 |
Combinatorial approaches towards the discovery of new tryptase inhibitors. |
University of Barcelona |
15546728 |
15 |
Design of bivalent ligands using hydrogen bond linkers: synthesis and evaluation of inhibitors for human beta-tryptase. |
Aventis Pharmaceuticals |
15341931 |
15 |
Novel pyrazinone inhibitors of mast cell tryptase: synthesis and SAR evaluation. |
Aventis Pharmaceuticals |
11959009 |
7 |
Bivalent inhibition of beta-tryptase: distance scan of neighboring subunits by dibasic inhibitors. |
Institut FüR Biochemie |
11527724 |
30 |
Monocharged inhibitors of mast cell tryptase derived from potent and selective dibasic inhibitors. |
Axys Pharmaceuticals |
11055355 |
72 |
Dibasic inhibitors of human mast cell tryptase. Part 1: synthesis and optimization of a novel class of inhibitors. |
Axys Pharmaceuticals |
27563406 |
128 |
Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors. |
Roche Pharma Research and Early Development |
30995036 |
52 |
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway. |
Novartis Institutes For Biomedical Research |