47 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
26395057	48	From carbohydrates to drug-like fragments: Rational development of novela-amylase inhibitors.	Freie Universit£T Berlin
26112442	74	Synthesis and biological evaluation of 3,5-disubstituted-4-alkynylisoxozales as a novel class of HSP90 inhibitors.	Chengdu University of Tcm
25901531	211	Structure-activity relationship in a purine-scaffold compound series with selectivity for the endoplasmic reticulum Hsp90 paralog Grp94.	Sloan-Kettering Institute For Cancer Research
24984936	28	Potential C-terminal-domain inhibitors of heat shock protein 90 derived from a C-terminal peptide helix.	Tufts University
24980703	296	Fragment-based hit discovery and structure-based optimization of aminotriazoloquinazolines as novel Hsp90 inhibitors.	Nerviano Medical Sciences
24745965	22	Towards the discovery of drug-like epigallocatechin gallate analogs as Hsp90 inhibitors.	Montclair State University
24580531	6	Differences in conformational dynamics between Plasmodium falciparum and human Hsp90 orthologues enable the structure-based discovery of pathogen-selective inhibitors.	University of Geneva
24763261	35	Identification and optimization of novel Hsp90 inhibitors with tetrahydropyrido[4,3-d]pyrimidines core through shape-based screening.	China Pharmaceutical University
24673104	185	Identification of novel HSP90a/ß isoform selective inhibitors using structure-based drug design. demonstration of potential utility in treating CNS disorders such as Huntington's disease.	Vertex Pharmaceuticals
23394126	170	Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR).	Exelixis
23186287	1	Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis.	Seoul National University
22835870	29	Modulation of DNA repair by pharmacological inhibitors of the PIKK protein kinase family.	Astrazeneca
23018093	41	Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization.	Vernalis
22632933	65	Fragment-based discovery of hydroxy-indazole-carboxamides as novel small molecule inhibitors of Hsp90.	Merck Serono
22386527	23	Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90.	Serenex
20055425	29	Heat shock protein 90: inhibitors in clinical trials.	Biogen Idec
19405528	45	Potent cytotoxic C-11 modified geldanamycin analogues.	Kosan Biosciences
19017562	45	Discovery and development of heat shock protein 90 inhibitors.	Memorial Sloan-Kettering Cancer Center
22066525	65	Novel 3,4-isoxazolediamides as potent inhibitors of chaperone heat shock protein 90.	Universit£
22014826	3	A small molecule that preferentially binds the closed conformation of Hsp90.	San Diego State University
21972823	10	Tricyclic series of heat shock protein 90 (Hsp90) inhibitors part I: discovery of tricyclic imidazo[4,5-c]pyridines as potent inhibitors of the Hsp90 molecular chaperone.	Sanofi-Aventis Research and Development
21920765	12	Lead identification ofß-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90.	Trinity College
20608738	7	ATPases as drug targets: insights from heat shock proteins 70 and 90.	Vernalis R&D
19331414	1	Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin.	Trinity College
18457385	41	Recent developments in fragment-based drug discovery.	Astex Therapeutics
16392823	39	Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.	Memorial Sloan-Kettering Cancer Center
27312008	4	Inhibition of Plasmodium falciparum Hsp90 Contributes to the Antimalarial Activities of Aminoalcohol-carbazoles.	Universit£
31663736	15	Heat Shock Protein 90 Inhibitors: An Update on Achievements, Challenges, and Future Directions.	China Pharmaceutical University
24582477	33	Synthesis and evaluation of a novel class Hsp90 inhibitors containing 1-phenylpiperazine scaffold.	China Pharmaceutical University
24548207	14	Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70.	Memorial Sloan-Kettering Cancer Center
24495105	1	Study of marine natural products including resorcyclic acid lactones from Humicola fuscoatra that reactivate latent HIV-1 expression in an in vitro model of central memory CD4+ T cells.	University of California
23770448	19	Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors.	University of Salerno
22591317	5	Impacts of some antibiotics on human serum paraoxonase 1 activity.	Atatürk University
14610240	8	Pharmacological and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine (AFM) and 3-amino-4-[2-(dimethylaminomethyl-phenylthio)]benzonitrile (DASB).	National Institutes of Health
10832613	26	[3H]S33084: a novel, selective and potent radioligand at cloned, human dopamine D3 receptors.	Croissy-Sur-Seine Paris