The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28112927 |
34 |
Selective Inhibitors of Human Liver Carboxylesterase Based on aß-Lapachone Scaffold: Novel Reagents for Reaction Profiling. |
St. Jude Children'S Research Hospital |
26900660 |
35 |
Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2. |
Dalian Institute of Chemical Physics |
23386702 |
10 |
Reversible inhibition of human carboxylesterases by acyl glucuronides. |
Eisai |
23286284 |
50 |
Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen"). |
St. Jude Children'S Research Hospital |
19062296 |
63 |
Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis. |
Kyoto University |
19534556 |
57 |
Improved, selective, human intestinal carboxylesterase inhibitors designed to modulate 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (Irinotecan; CPT-11) toxicity. |
St. Jude Children'S Research Hospital |
18630870 |
236 |
Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase. |
Institute For Chemical Biology |
18247553 |
174 |
Optimization of alpha-ketooxazole inhibitors of fatty acid amide hydrolase. |
The Scripps Research Institute |
18023188 |
86 |
Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH). |
University of California |
17279740 |
191 |
Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. |
The Scripps Research Institute |
21733699 |
121 |
Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones. |
St. Jude Children'S Research Hospital |
21105730 |
30 |
Structure-activity relationships of substituted 1-pyridyl-2-phenyl-1,2-ethanediones: potent, selective carboxylesterase inhibitors. |
St. Jude Children'S Research Hospital |
18639454 |
55 |
Exploration of a fundamental substituent effect of alpha-ketoheterocycle enzyme inhibitors: Potent and selective inhibitors of fatty acid amide hydrolase. |
The Scripps Research Institute |
17399985 |
136 |
Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils. |
St. Jude Children'S Research Hospital |
16107154 |
41 |
Inhibition of carboxylesterases by benzil (diphenylethane-1,2-dione) and heterocyclic analogues is dependent upon the aromaticity of the ring and the flexibility of the dione moiety. |
St. Jude Children'S Research Hospital |
15771430 |
129 |
Discovery of a potent, selective, and efficacious class of reversible alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesics. |
The Scripps Research Institute |
15713400 |
99 |
Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency and selectivity. |
The Scripps Research Institute |
32058719 |
22 |
Yanhusanines A-F, Isoquinoline-Derived Alkaloid Enantiomers from |
Chinese Academy of Medical Sciences and Peking Union Medical College |
26827140 |
83 |
Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors. |
Institute of Physiologically Active Compounds Russian Academy of Sciences |
30351923 |
12 |
Potent, Irreversible Inhibition of Human Carboxylesterases by Tanshinone Anhydrides Isolated from Salvia miltiorrhiza ("Danshen"). |
St. Jude Children'S Research Hospital |
30093295 |
3 |
Evaluation of 4-phenylamino-substituted naphthalene-1,2-diones as tubulin polymerization inhibitors. |
South China University of Technology |
29499489 |
18 |
Facile synthesis of 1,2-dione-containing abietane analogues for the generation of human carboxylesterase inhibitors. |
St. Jude Children'S Research Hospital |
29366648 |
98 |
Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. |
University of California Davis |
29353723 |
7 |
Bysspectin A, an unusual octaketide dimer and the precursor derivatives from the endophytic fungus Byssochlamys spectabilis IMM0002 and their biological activities. |
Chinese Academy of Medical Sciences and Peking Union Medical College |
21168763 |
9 |
Natural product-guided discovery of a fungal chitinase inhibitor. |
University of Dundee |