The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
1347319 |
15 |
Synthesis and alpha-adrenergic activities of 2- and 4-substituted imidazoline and imidazole analogues. |
Ohio State University |
1671705 |
126 |
Structure-affinity relationships of 12-sulfonyl derivatives of 5,8,8a,9,10,11,12,12a,13,13a-decahydro-6H-isoquino[2,1-g][1 ,6] naphthyridines at alpha-adrenoceptors. |
Syntex Research |
2542561 |
48 |
New 1,4-dihydropyridine derivatives combining calcium antagonism and alpha-adrenolytic properties. |
Institut De Pharmacologie (Ua 589 Cnrs) |
3037080 |
8 |
Radioiodinated p-iodoclonidine: a high-affinity probe for the alpha 2-adrenergic receptor. |
TBA |
2879916 |
20 |
Conformationally defined adrenergic agents. 4. 1-(aminomethyl)phthalans: synthesis and pharmacological consequences of the phthalan ring oxygen atom. |
TBA |
3020250 |
4 |
Synthesis and adrenergic activity of ring-fluorinated phenylephrines. |
TBA |
6330361 |
6 |
Development of an affinity ligand for purification of alpha 2-adrenoceptors from human platelet membranes. |
TBA |
26099069 |
15 |
Therapeutic Potential of 5-HT6 Receptor Agonists. |
Universit£ |
25521963 |
38 |
Synthesis and biological evaluation of 2-aryliminopyrrolidines as selective ligands for I1 imidazoline receptors: discovery of new sympatho-inhibitory hypotensive agents with potential beneficial effects in metabolic syndrome. |
Universit£ |
25490760 |
45 |
a2-adrenoceptor antagonists: synthesis, pharmacological evaluation, and molecular modeling investigation of pyridinoguanidine, pyridino-2-aminoimidazoline and their derivatives. |
Trinity College |
25343529 |
221 |
Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: synthesis, biological characterization, and behavioral studies. |
Universit£ |
16451077 |
86 |
Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists. |
Pfizer |
15482914 |
25 |
Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750. |
Pfizer |
14998318 |
112 |
Selective optimization of side activities: another way for drug discovery. |
Prestwick Chemical |
1833546 |
47 |
Synthesis and pharmacological evaluation of 1-(aminomethyl)-3,4-dihydro-5-hydroxy-1H-2-benzopyrans as dopamine D1 selective ligands. |
Abbott Laboratories |
2845082 |
35 |
Syntheses and adrenergic activities of ring-fluorinated epinephrines. |
National Institute of Diabetes |
2982020 |
2 |
N-[2-hydroxy-5-[2-(methylamino)ethyl]phenyl]methanesulfonamide. A potent agonist which releases intracellular calcium by activation of alpha 1-adrenoceptors. |
TBA |
15203136 |
39 |
(+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents. |
Virginia Commonwealth University |
| 32 |
The synthesis and biological activity of some known and putative metabolites of the atypical antipsychotic agent olanzapine (LY170053) |
TBA |
| 37 |
The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists. |
TBA |
15341484 |
159 |
Synthesis and structure--activity relationship in a class of indolebutylpiperazines as dual 5-HT(1A) receptor agonists and serotonin reuptake inhibitors. |
Merck |
15341483 |
110 |
Indolebutylamines as selective 5-HT(1A) agonists. |
Merck |
15149647 |
10 |
Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist. |
Pfizer |
14611858 |
65 |
1H-Pyrazolo-[3,4-c]cyclophepta[1,2-c]thiophenes: a unique structural class of dopamine D4 selective ligands. |
Neurogen |
27474922 |
16 |
Substituted conformationally restricted guanidine derivatives: Probing the ?2-adrenoceptors' binding pocket. |
Trinity College |
19133776 |
17 |
Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor ligands: searching for structure-activity relationships. |
University of Dublin |
17691718 |
28 |
Guanidine and 2-aminoimidazoline aromatic derivatives as alpha(2)-adrenoceptor antagonists, 1: toward new antidepressants with heteroatomic linkers. |
University of Dublin |
12747788 |
41 |
Imidazoline binding sites (IBS) profile modulation: key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues. |
Universit£ |
8709134 |
26 |
Medetomidine analogs as alpha 2-adrenergic ligands. 2. Design, synthesis, and biological activity of conformationally restricted naphthalene derivatives of medetomidine. |
Ohio State University |
8057272 |
33 |
Evolution of a novel series of [(N,N-dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT1D antagonists. |
Glaxo Research and Development |
28644987 |
24 |
Thiophene/thiazole-benzene replacement on guanidine derivatives targeting? |
Trinity College |
28489950 |
119 |
Return of D |
University of Nebraska Medical Center |
| 31 |
Novel 2(3H)-benzothiazolones as highly potent and selective sigma-1 receptor ligands |
Universite De Lille |