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37 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
1347319 15 Synthesis and alpha-adrenergic activities of 2- and 4-substituted imidazoline and imidazole analogues.EBI Ohio State University
1671705 126 Structure-affinity relationships of 12-sulfonyl derivatives of 5,8,8a,9,10,11,12,12a,13,13a-decahydro-6H-isoquino[2,1-g][1 ,6] naphthyridines at alpha-adrenoceptors.EBI Syntex Research
2542561 48 New 1,4-dihydropyridine derivatives combining calcium antagonism and alpha-adrenolytic properties.EBI Institut De Pharmacologie (Ua 589 Cnrs)
3037080 8 Radioiodinated p-iodoclonidine: a high-affinity probe for the alpha 2-adrenergic receptor.EBI TBA
2879916 20 Conformationally defined adrenergic agents. 4. 1-(aminomethyl)phthalans: synthesis and pharmacological consequences of the phthalan ring oxygen atom.EBI TBA
3020250 4 Synthesis and adrenergic activity of ring-fluorinated phenylephrines.EBI TBA
6330361 6 Development of an affinity ligand for purification of alpha 2-adrenoceptors from human platelet membranes.EBI TBA
26099069 15 Therapeutic Potential of 5-HT6 Receptor Agonists.EBI Universit£
25521963 38 Synthesis and biological evaluation of 2-aryliminopyrrolidines as selective ligands for I1 imidazoline receptors: discovery of new sympatho-inhibitory hypotensive agents with potential beneficial effects in metabolic syndrome.EBI Universit£
25490760 45 a2-adrenoceptor antagonists: synthesis, pharmacological evaluation, and molecular modeling investigation of pyridinoguanidine, pyridino-2-aminoimidazoline and their derivatives.EBI Trinity College
25343529 221 Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: synthesis, biological characterization, and behavioral studies.EBI Universit£
16451077 86 Pyrrolizidine esters and amides as 5-HT4 receptor agonists and antagonists.EBI Pfizer
15482914 25 Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.EBI Pfizer
14998318 112 Selective optimization of side activities: another way for drug discovery.EBI Prestwick Chemical
1833546 47 Synthesis and pharmacological evaluation of 1-(aminomethyl)-3,4-dihydro-5-hydroxy-1H-2-benzopyrans as dopamine D1 selective ligands.EBI Abbott Laboratories
2845082 35 Syntheses and adrenergic activities of ring-fluorinated epinephrines.EBI National Institute of Diabetes
2982020 2 N-[2-hydroxy-5-[2-(methylamino)ethyl]phenyl]methanesulfonamide. A potent agonist which releases intracellular calcium by activation of alpha 1-adrenoceptors.EBI TBA
15203136 39 (+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents.EBI Virginia Commonwealth University
 32 The synthesis and biological activity of some known and putative metabolites of the atypical antipsychotic agent olanzapine (LY170053)EBI TBA
 37 The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists.EBI TBA
15341484 159 Synthesis and structure--activity relationship in a class of indolebutylpiperazines as dual 5-HT(1A) receptor agonists and serotonin reuptake inhibitors.EBI Merck
15341483 110 Indolebutylamines as selective 5-HT(1A) agonists.EBI Merck
15149647 10 Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist.EBI Pfizer
14611858 65 1H-Pyrazolo-[3,4-c]cyclophepta[1,2-c]thiophenes: a unique structural class of dopamine D4 selective ligands.EBI Neurogen
27474922 16 Substituted conformationally restricted guanidine derivatives: Probing the ?2-adrenoceptors' binding pocket.EBI Trinity College
19133776 17 Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor ligands: searching for structure-activity relationships.EBI University of Dublin
17691718 28 Guanidine and 2-aminoimidazoline aromatic derivatives as alpha(2)-adrenoceptor antagonists, 1: toward new antidepressants with heteroatomic linkers.EBI University of Dublin
12747788 41 Imidazoline binding sites (IBS) profile modulation: key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues.EBI Universit£
8709134 26 Medetomidine analogs as alpha 2-adrenergic ligands. 2. Design, synthesis, and biological activity of conformationally restricted naphthalene derivatives of medetomidine.EBI Ohio State University
8057272 33 Evolution of a novel series of [(N,N-dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT1D antagonists.EBI Glaxo Research and Development
28644987 24 Thiophene/thiazole-benzene replacement on guanidine derivatives targeting?EBI Trinity College
28489950 119 Return of DEBI University of Nebraska Medical Center
 31 Novel 2(3H)-benzothiazolones as highly potent and selective sigma-1 receptor ligandsBDB Universite De Lille