The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28002667 |
51 |
Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe. |
Glaxosmithkline |
| 27994766 |
28 |
Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening. |
University of Dundee |
| 27682507 |
167 |
Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300. |
Genentech |
| 26701186 |
50 |
KATching-Up on Small Molecule Modulators of Lysine Acetyltransferases. |
University of Freiburg |
| 26731131 |
2 |
Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain. |
University of Oxford |
| 26230603 |
176 |
Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain Inhibitors. |
Glaxosmithkline |
| 25730130 |
20 |
A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach. |
Universit£ |
| 25249180 |
146 |
The discovery of I-BET726 (GSK1324726A), a potent tetrahydroquinoline ApoA1 up-regulator and selective BET bromodomain inhibitor. |
Glaxosmithkline |
| 24345448 |
4 |
Azide-alkyne cycloaddition affording enzymatically tunable bisubstrate based inhibitors of histone acetyltransferase PCAF. |
Utrecht University |
| 24144283 |
100 |
Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains. |
Icahn School of Medicine At Mount Sinai |
| 22924434 |
4 |
Progress in the development and application of small molecule inhibitors of bromodomain-acetyl-lysine interactions. |
University of Oxford |
| 19114310 |
30 |
Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60. |
Georgia State University |
| 19101154 |
28 |
Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs). |
The Institute of Cancer Research |
| 22100137 |
6 |
6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site. |
University of Groningen |
| 21353783 |
37 |
Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. |
Albert-Ludwigs-University of Freiburg |
| 20655754 |
2 |
Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative. |
Groningen Research Institute of Pharmacy |
| 19683843 |
16 |
Reactivity of isothiazolones and isothiazolone-1-oxides in the inhibition of the PCAF histone acetyltransferase. |
University of Groningen |
| 19111471 |
19 |
Inhibition of the PCAF histone acetyl transferase and cell proliferation by isothiazolones. |
University of Groningen |
| 28949521 |
88 |
Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor. |
Abbvie |
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