The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
24462665 |
30 |
Discovery of novel indazole derivatives as dual angiotensin II antagonists and partial PPAR¿ agonists. |
Glaxosmithkline |
22369181 |
6 |
(Z)-2-(2-bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): an orally bioavailable PPARß/d-selective ligand with inverse agonistic properties. |
Philipps University |
22133631 |
76 |
Discovery of cyclic amine-substituted benzoic acids as PPARa agonists. |
Kyorin Pharmaceutical |
21074432 |
25 |
Selective peroxisome proliferator-activated receptord isosteric selenium agonists as potent anti-atherogenic agents in vivo. |
Seoul National University |
20822906 |
11 |
A stereo-controlled synthesis of 2,4-dimethyl-4-hydroxy-16-phenylhexadecanoic acid 1,4-lactone and its PPAR activities. |
Seoul National University |
20452212 |
26 |
Glycine amides as PPARalpha agonists. |
Bayer-Schering Pharma |
19928766 |
425 |
Novel bisaryl substituted thiazoles and oxazoles as highly potent and selective peroxisome proliferator-activated receptor delta agonists. |
The Genomics Institute of The Novartis Research Foundation |
20079636 |
78 |
Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators. |
Glaxosmithkline |
18947994 |
102 |
The discovery of equipotent PPARalpha/gamma dual activators. |
Glaxosmithkline |
18060776 |
100 |
Design, synthesis and evaluation of trifluoromethane sulfonamide derivatives as new potent and selective peroxisome proliferator-activated receptor alpha agonists. |
Glaxosmithkline |
17343371 |
27 |
Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo. |
Novo Nordisk |
17157013 |
74 |
Indanylacetic acid derivatives carrying aryl-pyridyl and aryl-pyrimidinyl tail groups--new classes of PPAR gamma/delta and PPAR alpha/gamma/delta agonists. |
Bayer Pharmaceuticals |
16275077 |
27 |
Design and synthesis of substituted phenylpropanoic acid derivatives as human peroxisome proliferator-activated receptor alpha/delta dual agonists. |
University of Tokyo |
12699745 |
49 |
Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity. |
Glaxosmithkline |
11677135 |
21 |
Identification of a series of PPAR gamma/delta dual agonists via solid-phase parallel synthesis. |
Glaxosmithkline |
11354382 |
42 |
Identification of a subtype selective human PPARalpha agonist through parallel-array synthesis. |
Glaxosmithkline |
10691680 |
72 |
The PPARs: from orphan receptors to drug discovery. |
Glaxo Wellcome Research & Development |
10508427 |
42 |
A ureido-thioisobutyric acid (GW9578) is a subtype-selective PPARalpha agonist with potent lipid-lowering activity. |
Glaxo Wellcome Research & Development |
30594433 |
90 |
Discovery of potent and selective PPAR?/? dual antagonists and initial biological studies. |
Inception Sciences |
29446942 |
98 |
Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR)?/?/? Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate. |
Inventiva |