The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28603989 |
53 |
a-Conotoxin [S9A]TxID Potently Discriminates betweena3ß4 anda6/a3ß4 Nicotinic Acetylcholine Receptors. |
Hainan University |
28337332 |
41 |
BMS-933043, a Selectivea7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia. |
Bristol-Myers Squibb |
27958732 |
93 |
Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes asa7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure-Activity Relationship. |
Bristol-Myers Squibb |
27639361 |
88 |
Synthesis and biological evaluation of novel hybrids of highly potent and selectivea4ß2-Nicotinic acetylcholine receptor (nAChR) partial agonists. |
University of Illinois At Chicago |
24844195 |
21 |
Synthesis and pharmacological characterization of new neuronal nicotinic acetylcholine receptor ligands derived from Sazetidine-A. |
Georgetown University Medical Center |
24187998 |
96 |
Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists. |
University of Copenhagen |
24649848 |
47 |
Discovery of a potent and selectivea3ß4 nicotinic acetylcholine receptor antagonist from ana-conotoxin synthetic combinatorial library. |
Torrey Pines Institute For Molecular Studies |
15050615 |
36 |
Synthesis and pharmacological characterization of bivalent ligands of epibatidine at neuronal nicotinic acetylcholine receptors. |
University of Illinois At Chicago |
24428686 |
6 |
Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted pyridinyl)-7-deschloroepibatidine analogues. |
Research Triangle Institute |
24274400 |
28 |
Scaffold ranking and positional scanning utilized in the discovery of nAChR-selective compounds suitable for optimization studies. |
Torrey Pines Institute For Molecular Studies |
24200193 |
32 |
Characterization of a novela-conotoxin TxID from Conus textile that potently blocks rata3ß4 nicotinic acetylcholine receptors. |
Hainan University |
24047231 |
52 |
Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands. |
Georgetown University |
15686946 |
36 |
Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors. |
National Institute of Diabetes and Digestive and Kidney Diseases |
22410083 |
17 |
Consequences of linker length alteration of thea7 nicotinic acetylcholine receptor (nAChR) agonist, SEN12333. |
The University of Sydney |
15050613 |
50 |
Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells. |
Georgetown University School of Medicine |
20979364 |
40 |
Novela3ß4 nicotinic acetylcholine receptor-selective ligands. Discovery, structure-activity studies, and pharmacological evaluation. |
Sri International |
16005216 |
20 |
The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion. |
University of Florida |
15771418 |
38 |
Novel pyridyl ring C5 substituted analogues of epibatidine and 3-(1-methyl-2(S)-pyrrolidinylmethoxy)pyridine (A-84543) as highly selective agents for neuronal nicotinic acetylcholine receptors containing beta2 subunits. |
University of Illinois At Chicago |
15050621 |
100 |
Epibatidine structure-activity relationships. |
Research Triangle Institute |
31986036 |
89 |
Structure and Activity Studies of Disulfide-Deficient Analogues of ?O-Conotoxin GeXIVA. |
Hainan University |
31194549 |
57 |
PeIA-5466: A Novel Peptide Antagonist Containing Non-natural Amino Acids That Selectively Targets ?3?2 Nicotinic Acetylcholine Receptors. |
Veterans Affairs Medical Center |
26298493 |
133 |
Conformationally restrained carbamoylcholine homologues. Synthesis, pharmacology at neuronal nicotinic acetylcholine receptors and biostructural considerations. |
Iqm-Csic |
25050162 |
78 |
Synthesis and Pharmacological Evaluation of DH?E Analogues as Neuronal Nicotinic Acetylcholine Receptor Antagonists. |
University of Copenhagen |
25464883 |
11 |
Synthesis, in vitro and in vivo studies, and molecular modeling of N-alkylated dextromethorphan derivatives as non-competitive inhibitors of ?3?4 nicotinic acetylcholine receptor. |
Medical University of Lublin |
16640326 |
104 |
Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity. |
University of Illinois At Chicago |
16039849 |
84 |
Epibatidine analogues as selective ligands for the alpha(x)beta2-containing subtypes of nicotinic acetylcholine receptors. |
Columbia University College of Physicians and Surgeons |
16078832 |
25 |
Ligand selectivity for the acetylcholine binding site of the rat alpha4beta2 and alpha3beta4 nicotinic subtypes investigated by molecular docking. |
Swiss Federal Institute of Technology Zurich |
15925512 |
23 |
6-(2-Phenylethyl)nicotine: a novel nicotinic cholinergic receptor ligand. |
Virginia Commonwealth University |
12620069 |
42 |
Synthesis, nicotinic acetylcholine receptor binding affinities, and molecular modeling of constrained epibatidine analogues. |
Georgetown University Medical Center |
29671588 |
35 |
Absolute Configuration and Pharmacology of the Poison Frog Alkaloid Phantasmidine. |
Indiana State University |
30252466 |
37 |
Single Amino Acid Substitution in ?-Conotoxin TxID Reveals a Specific ?3?4 Nicotinic Acetylcholine Receptor Antagonist. |
Hainan University |
29050783 |
40 |
Design and synthesis of a novel series of (1'S,2R,4'S)-3H-4'-azaspiro[benzo[4,5]imidazo[2,1-b]oxazole-2,2'-bicyclo[2.2.2]octanes] with high affinity for the ?7 neuronal nicotinic receptor. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
29384668 |
249 |
Dual Nicotinic Acetylcholine Receptor ?4?2 Antagonists/?7 Agonists: Synthesis, Docking Studies, and Pharmacological Evaluation of Tetrahydroisoquinolines and Tetrahydroisoquinolinium Salts. |
University of Copenhagen |
29178785 |
61 |
Highly Selective and Potent?4?2 nAChR Antagonist Inhibits Nicotine Self-Administration and Reinstatement in Rats. |
Torrey Pines Institute For Molecular Studies |