The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28259841 |
9 |
Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: The case of trifluoroacetylation. |
Aristotle University of Thessaloniki |
| 28109789 |
22 |
Synthesis and structure-activity relationship studies of phenolic hydroxyl derivatives based on quinoxalinone as aldose reductase inhibitors with antioxidant activity. |
Beijing Institute of Technology |
| 27639366 |
41 |
Design and synthesis of chiral 2H-chromene-N-imidazolo-amino acid conjugates as aldose reductase inhibitors. |
Osmania University |
| 27156769 |
12 |
Synthesis of benzothiadiazine derivatives exhibiting dual activity as aldose reductase inhibitors and antioxidant agents. |
Beijing Institute of Technology |
| 26331986 |
6 |
Phenolic Compounds from the Leaves and Twigs of Osteomeles schwerinae That Inhibit Rat Lens Aldose Reductase and Vessel Dilation in Zebrafish Larvae. |
Institute of Oriental Medicine |
| 25695864 |
35 |
Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold. |
Slovak Academy of Sciences |
| 24780598 |
7 |
Synthesis and biological evaluation of some new pyrazoline substituted benzenesulfonylurea/thiourea derivatives as anti-hyperglycaemic agents and aldose reductase inhibitors. |
Jamia Hamdard (Hamdard University) |
| 24630695 |
11 |
Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation. |
Aristotle University of Thessaloniki |
| 24275248 |
6 |
Synthesis and biological evaluation of new epalrestat analogues as aldose reductase inhibitors (ARIs). |
Csir-Indian Institute of Chemical Technology |
| 23891165 |
12 |
1-Hydroxypyrazole as a bioisostere of the acetic acid moiety in a series of aldose reductase inhibitors. |
Aristotle University of Thessaloniki |
| 23312612 |
8 |
Synthesis of derivatives of the keto-pyrrolyl-difluorophenol scaffold: some structural aspects for aldose reductase inhibitory activity and selectivity. |
Aristotle University of Thessaloniki |
| 18585047 |
59 |
QSAR prediction of inhibition of aldose reductase for flavonoids. |
Inifta (Unlp, Cct La Plata-Conicet) |
| 22224640 |
53 |
Update on the development of antagonists of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2). From lead optimization to clinical proof-of-concept in asthma and allergic rhinitis. |
Oxagen |
| 22264115 |
19 |
Chemical constituents from the aerial parts of Aster koraiensis with protein glycation and aldose reductase inhibitory activities. |
Korean Institute of Oriental Medicine (Kiom) |
| 19670875 |
19 |
Inhibitors of aldose reductase and formation of advanced glycation end-products in moutan cortex (Paeonia suffruticosa). |
Chungnam National University |
| 18298080 |
10 |
Erigeroflavanone, a flavanone derivative from the flowers of Erigeron annuus with protein glycation and aldose reductase inhibitory activity. |
Institute of Oriental Medicine |
| 14510595 |
25 |
Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis. |
Kyoto Pharmaceutical University |
| 18087047 |
3 |
Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10. |
Universitat Aut£Noma De Barcelona |
| 12540241 |
5 |
Substituted pyrrol-1-ylacetic acids that combine aldose reductase enzyme inhibitory activity and ability to prevent the nonenzymatic irreversible modification of proteins from monosaccharides. |
Aristotle University of Thessaloniki |
| 8145228 |
15 |
Molecular modeling studies of aldose reductase inhibitors. |
National Eye Institute |
| 1900532 |
44 |
A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, and its congeners. |
Pfizer |
| 1956041 |
28 |
Spiro[fluoreneisothiazolidin]one dioxides: new aldose reductase and L-hexonate dehydrogenase inhibitors. |
Alcon Laboratories |
| 2491890 |
62 |
N- and 2-substituted N-(phenylsulfonyl)glycines as inhibitors of rat lens aldose reductase. |
Auburn University |
| 3086557 |
19 |
Synthesis and rat lens aldose reductase inhibitory activity of some benzopyran-2-ones. |
TBA |
| 3093680 |
13 |
Synthesis and aldose reductase inhibitory activity of substituted 2-oxoquinoline-1-acetic acid derivatives. |
TBA |
| 22261024 |
21 |
Construction of an Indonesian herbal constituents database and its use in Random Forest modelling in a search for inhibitors of aldose reductase. |
King'S College London |
| 22209731 |
81 |
Antidiabetogenic oligostilbenoids and 3-ethyl-4-phenyl-3,4-dihydroisocoumarins from the bark of Shorea roxburghii. |
Kinki University |
| 22036211 |
4 |
1,2-Benzothiazine 1,1-dioxide carboxylate derivatives as novel potent inhibitors of aldose reductase. |
Beijing Institute of Technology |
| 21944852 |
79 |
Substituted indole-1-acetic acids as potent and selective CRTh2 antagonists-discovery of AZD1981. |
Astrazeneca R&D Charnwood |
| 21288726 |
7 |
Structure-activity relations on [1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone. The effect of methoxy substitution on aldose reductase inhibitory activity and selectivity. |
Aristotle University of Thessaloniki |
| 21062005 |
12 |
Acetic Acid Derivatives of 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxide as a Novel Class of Potent Aldose Reductase Inhibitors |
TBA |
| 20936791 |
32 |
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity. |
Aristotle University of Thessaloniki |
| 19962793 |
14 |
Synthesis and biological evaluation of [1,2,4]triazino[4,3-a] benzimidazole acetic acid derivatives as selective aldose reductase inhibitors. |
Institute of Pharmaceutical Sciences |
| 20189816 |
8 |
Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole. |
Aristotle University of Thessaloniki |
| 18565754 |
4 |
Synthesis and biological activity of some new flavonyl-2,4-thiazolidinediones. |
Ankara University |
| 18313804 |
6 |
Synthesis and aldose reductase inhibitory activity of some new chromonyl-2,4-thiazolidinediones. |
Ankara University |
| 18267362 |
9 |
Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors. |
Aristotle University of Thessaloniki |
| 12193020 |
9 |
New flavonol oligoglycosides and polyacylated sucroses with inhibitory effects on aldose reductase and platelet aggregation from the flowers of Prunus mume. |
Kyoto Pharmaceutical University |
| 17845019 |
21 |
Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity. |
Università |
| 16753296 |
25 |
Discovery of potent CRTh2 (DP2) receptor antagonists. |
Astrazeneca R&D Charnwood |
| 16107153 |
10 |
Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. |
Monash University (Parkville Campus) |
| 15115413 |
4 |
[1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone as a bioisostere of a carboxylic acid aldose reductase inhibitor. |
Aristotle University of Thessaloniki |
| 12672241 |
37 |
Novel, highly potent aldose reductase inhibitors: cyano(2-oxo-2,3-dihydroindol-3-yl)acetic acid derivatives. |
Università |
| 11728182 |
28 |
[1,2,4]Triazino[4,3-a]benzimidazole acetic acid derivatives: a new class of selective aldose reductase inhibitors. |
Università |
| 32192796 |
25 |
Novel quinolin-4(1H)-one derivatives as multi-effective aldose reductase inhibitors for treatment of diabetic complications: Synthesis, biological evaluation, and molecular modeling studies. |
Institute of Technology |
| 10882376 |
7 |
A potent aldose reductase inhibitor, (2S,4S)-6-fluoro-2', 5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide (Fidarestat): its absolute configuration and interactions with the aldose reductase by X-ray crystallography. |
Rational Drug Design Laboratories |
| 30858026 |
31 |
Designing of acyl sulphonamide based quinoxalinones as multifunctional aldose reductase inhibitors. |
Beijing Institute of Technology |
| 30818176 |
64 |
Synthesis of new arylsulfonylspiroimidazolidine-2',4'-diones and study of their effect on stimulation of insulin release from MIN6 cell line, inhibition of human aldose reductase, sorbitol accumulations in various tissues and oxidative stress. |
Quaid-I-Azam University |
| 31820975 |
19 |
Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity. |
Comenius University In Bratislava |
| 9057855 |
33 |
Highly selective aldose reductase inhibitors. 3. Structural diversity of 3-(arylmethyl)-2,4,5-trioxoimidazolidine-1-acetic acids. |
Nippon Zoki Pharmaceutical |
| 8627616 |
12 |
Highly selective aldose reductase inhibitors. 1. 3-(Arylalkyl)-2,4,5-trioxoimidazolidine-1-acetic acids. |
Nippon Zoki Pharmaceutical |
| 26227780 |
8 |
Phenolic 4-hydroxy and 3,5-dihydroxy derivatives of 3-phenoxyquinoxalin-2(1H)-one as potent aldose reductase inhibitors with antioxidant activity. |
Beijing Institute of Technology |
| 25602762 |
38 |
Design and synthesis of potent and multifunctional aldose reductase inhibitors based on quinoxalinones. |
Birla Institute of Technology |
| 24793885 |
11 |
Structure-activity relationships studies of quinoxalinone derivatives as aldose reductase inhibitors. |
Beijing Institute of Technology |
| 23134227 |
13 |
Benzofuroxane derivatives as multi-effective agents for the treatment of cardiovascular diabetic complications. Synthesis, functional evaluation, and molecular modeling studies. |
Universit£ |
| 22436396 |
30 |
Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step. |
Universit£ |
| 21367494 |
16 |
Design and synthesis of potent and selective aldose reductase inhibitors based on pyridylthiadiazine scaffold. |
Beijing Institute of Technology |
| 19719141 |
12 |
Pursuing aldose reductase inhibitors through in situ cross-docking and similarity-based virtual screening. |
Universita Di Napoli "Federico Ii |
| 18395454 |
12 |
Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling. |
Slovak Academy of Sciences |
| 17618015 |
13 |
Bioactive peroxides as potential therapeutic agents. |
The Hebrew University of Jerusalem |
| 3934383 |
6 |
Synthesis, absolute configuration, and conformation of the aldose reductase inhibitor sorbinil. |
TBA |
| 3925146 |
43 |
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications. |
TBA |
| 3114491 |
18 |
Novel inhibitors of rat lens aldose reductase: N-[[(substituted amino)phenyl]sulfonyl]glycines. |
TBA |
| 3097318 |
4 |
Synthesis and biological evaluation of irreversible inhibitors of aldose reductase. |
TBA |
| 3084783 |
6 |
Design and synthesis of 2-(arylamino)-4(3H)-quinazolinones as novel inhibitors of rat lens aldose reductase. |
TBA |
| 29074349 |
29 |
Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity. |
Slovak Academy of Sciences |
| 2539477 |
5 |
Computer-assisted design and synthesis of novel aldose reductase inhibitors. |
Wyeth-Ayerst Research |
| 2496229 |
34 |
Synthesis and in vitro aldose reductase inhibitory activity of compounds containing an N-acylglycine moiety. |
Auburn University |
| 28802633 |
2 |
1-Acetyl-5-phenyl-1H-pyrrol-3-ylacetate: An aldose reductase inhibitor for the treatment of diabetic nephropathy. |
Shanghai Institute of Pharmaceutical Industry |
| 1906108 |
27 |
Relative structure-inhibition analyses of the N-benzoyl and N-(phenylsulfonyl) amino acid aldose reductase inhibitors. |
Auburn University |
| 1899452 |
90 |
Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners. |
Pfizer |
| 28392277 |
22 |
N-(Aroyl)-N-(arylmethyloxy)-?-alanines: Selective inhibitors of aldose reductase. |
Universit£ |
| 1552504 |
8 |
Selective irreversible inhibitors of aldose reductase. |
Ohio State University |
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