The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26710088 |
248 |
Recent Progress in Histone Demethylase Inhibitors. |
University of Oxford |
26771107 |
113 |
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives. |
Glaxosmithkline |
26741168 |
239 |
8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. |
The Institute of Cancer Research |
26771203 |
114 |
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives. |
Glaxosmithkline |
22724510 |
84 |
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. |
University of Oxford |
30343192 |
10 |
Lysine demethylase 5B (KDM5B): A potential anti-cancer drug target. |
Zhengzhou University |
27499454 |
22 |
Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors. |
Genentech |
27476424 |
56 |
Identification of potent, selective KDM5 inhibitors. |
Constellation Pharmaceuticals |
27406798 |
92 |
Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies. |
Genentech |
30745098 |
24 |
Identification of novel lysine demethylase 5-selective inhibitors by inhibitor-based fragment merging strategy. |
Kyoto Prefectural University of Medicine |
31158747 |
257 |
C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays. |
Institute of Cancer Research |
26682034 |
229 |
Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor. |
University of Oxford |
24325601 |
74 |
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities. |
Sapienza University of Rome |
28512031 |
65 |
From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors. |
Genentech |
28160945 |
12 |
In search of new a-glucosidase inhibitors: Imidazolylpyrazole derivatives. |
University of The Punjab |