Found 229 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lysine-specific demethylase 6B
(Homo sapiens (Human)) | BDBM60875
(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)Show SMILES OC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1 Show InChI InChI=1S/C22H23N5O2/c28-21(29)8-12-24-19-15-20(26-22(25-19)18-7-3-4-11-23-18)27-13-9-16-5-1-2-6-17(16)10-14-27/h1-7,11,15H,8-10,12-14H2,(H,28,29)(H,24,25,26) | PDB
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| PDB
Article
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| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM6B (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM50498675
(CHEMBL3621881)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)[C@@H]1CCCN(C1)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C20H19N5O3/c26-19(14-5-2-1-3-6-14)24-10-4-7-16(12-24)25-13-18(22-23-25)17-11-15(20(27)28)8-9-21-17/h1-3,5-6,8-9,11,13,16H,4,7,10,12H2,(H,27,28)/t16-/m1/s1 | PDB
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| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 6B
(Homo sapiens (Human)) | BDBM50396018
(CHEMBL1230640)Show InChI InChI=1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14) | PDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM6B (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM50498680
(CHEMBL3621878)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCCN(C1)C(=O)c1ccccc1 Show InChI InChI=1S/C20H19N5O3/c26-19(14-5-2-1-3-6-14)24-10-4-7-16(12-24)25-13-18(22-23-25)17-11-15(20(27)28)8-9-21-17/h1-3,5-6,8-9,11,13,16H,4,7,10,12H2,(H,27,28) | PDB
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| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 3A
(Homo sapiens (Human)) | BDBM50396018
(CHEMBL1230640)Show InChI InChI=1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14) | Reactome pathway
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| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM3A (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4C
(Homo sapiens (Human)) | BDBM50498673
(CHEMBL3621852)Show InChI InChI=1S/C11H8N2O2/c14-11(15)8-4-6-13-10(7-8)9-3-1-2-5-12-9/h1-7H,(H,14,15) | PDB
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| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4C (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate incubated for 15 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5A
(Homo sapiens (Human)) | BDBM50498665
(CHEMBL1982368)Show InChI InChI=1S/C17H13ClN4/c18-14-9-10-16(20-12-14)21-22-17(13-6-2-1-3-7-13)15-8-4-5-11-19-15/h1-12H,(H,20,21)/b22-17+ | PDB
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| n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5A (unknown origin) by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4E
(Homo sapiens (Human)) | BDBM50396018
(CHEMBL1230640)Show InChI InChI=1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14) | PDB
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| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4E (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 6B
(Homo sapiens (Human)) | BDBM26106
(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Show InChI InChI=1S/C4H5NO5/c6-2(7)1-5-3(8)4(9)10/h1H2,(H,5,8)(H,6,7)(H,9,10) | PDB
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| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM6B (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Lysine-specific demethylase 4E
(Homo sapiens (Human)) | BDBM50498665
(CHEMBL1982368)Show InChI InChI=1S/C17H13ClN4/c18-14-9-10-16(20-12-14)21-22-17(13-6-2-1-3-7-13)15-8-4-5-11-19-15/h1-12H,(H,20,21)/b22-17+ | PDB
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| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4E (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4E
(Homo sapiens (Human)) | BDBM50498673
(CHEMBL3621852)Show InChI InChI=1S/C11H8N2O2/c14-11(15)8-4-6-13-10(7-8)9-3-1-2-5-12-9/h1-7H,(H,14,15) | PDB
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| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4E (unknown origin) by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM50498694
(CHEMBL3621872)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCN(C1)C(=O)c1ccccc1 Show InChI InChI=1S/C19H17N5O3/c25-18(13-4-2-1-3-5-13)23-9-7-15(11-23)24-12-17(21-22-24)16-10-14(19(26)27)6-8-20-16/h1-6,8,10,12,15H,7,9,11H2,(H,26,27) | PDB
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| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM26113
(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)Show InChI InChI=1S/C7H5NO4/c9-6(10)4-1-2-8-5(3-4)7(11)12/h1-3H,(H,9,10)(H,11,12) | PDB
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| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4C
(Homo sapiens (Human)) | BDBM50396018
(CHEMBL1230640)Show InChI InChI=1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14) | PDB
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| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4C (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM50498667
(CHEMBL3621880)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCCN(C1)C(=O)CCc1ccccc1 Show InChI InChI=1S/C22H23N5O3/c28-21(9-8-16-5-2-1-3-6-16)26-12-4-7-18(14-26)27-15-20(24-25-27)19-13-17(22(29)30)10-11-23-19/h1-3,5-6,10-11,13,15,18H,4,7-9,12,14H2,(H,29,30) | PDB
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| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498661
(CHEMBL3621865)Show InChI InChI=1S/C13H13N5O3/c1-8(19)17-5-10(6-17)18-7-12(15-16-18)11-4-9(13(20)21)2-3-14-11/h2-4,7,10H,5-6H2,1H3,(H,20,21) | PDB
MMDB
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| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498673
(CHEMBL3621852)Show InChI InChI=1S/C11H8N2O2/c14-11(15)8-4-6-13-10(7-8)9-3-1-2-5-12-9/h1-7H,(H,14,15) | PDB
MMDB
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| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 6B
(Homo sapiens (Human)) | BDBM50498665
(CHEMBL1982368)Show InChI InChI=1S/C17H13ClN4/c18-14-9-10-16(20-12-14)21-22-17(13-6-2-1-3-7-13)15-8-4-5-11-19-15/h1-12H,(H,20,21)/b22-17+ | PDB
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| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM6B (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM50498683
(CHEMBL3621873)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCN(C1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C20H19N5O3/c26-19(10-14-4-2-1-3-5-14)24-9-7-16(12-24)25-13-18(22-23-25)17-11-15(20(27)28)6-8-21-17/h1-6,8,11,13,16H,7,9-10,12H2,(H,27,28) | PDB
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| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4C
(Homo sapiens (Human)) | BDBM50498665
(CHEMBL1982368)Show InChI InChI=1S/C17H13ClN4/c18-14-9-10-16(20-12-14)21-22-17(13-6-2-1-3-7-13)15-8-4-5-11-19-15/h1-12H,(H,20,21)/b22-17+ | PDB
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| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4C (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498684
(CHEMBL3621870)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CN(C1)C(=O)CCc1ccccc1 Show InChI InChI=1S/C20H19N5O3/c26-19(7-6-14-4-2-1-3-5-14)24-11-16(12-24)25-13-18(22-23-25)17-10-15(20(27)28)8-9-21-17/h1-5,8-10,13,16H,6-7,11-12H2,(H,27,28) | PDB
MMDB
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KEGG
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| PC cid
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UniChem
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4A
(Homo sapiens (Human)) | BDBM50498673
(CHEMBL3621852)Show InChI InChI=1S/C11H8N2O2/c14-11(15)8-4-6-13-10(7-8)9-3-1-2-5-12-9/h1-7H,(H,14,15) | PDB
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| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4A (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 3A
(Homo sapiens (Human)) | BDBM50498673
(CHEMBL3621852)Show InChI InChI=1S/C11H8N2O2/c14-11(15)8-4-6-13-10(7-8)9-3-1-2-5-12-9/h1-7H,(H,14,15) | Reactome pathway
KEGG
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| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM3A (unknown origin) using H3(1-21)K9Me2-GGK-biotin substrate incubated for 5 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4C
(Homo sapiens (Human)) | BDBM50498661
(CHEMBL3621865)Show InChI InChI=1S/C13H13N5O3/c1-8(19)17-5-10(6-17)18-7-12(15-16-18)11-4-9(13(20)21)2-3-14-11/h2-4,7,10H,5-6H2,1H3,(H,20,21) | PDB
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antibodypedia
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| Article
PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4C (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate incubated for 15 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 3A
(Homo sapiens (Human)) | BDBM26106
(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)Show InChI InChI=1S/C4H5NO5/c6-2(7)1-5-3(8)4(9)10/h1H2,(H,5,8)(H,6,7)(H,9,10) | Reactome pathway
KEGG
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MCE
MMDB
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UniChem
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| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM3A (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498674
(CHEMBL3621874)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCN(C1)C(=O)CCc1ccccc1 Show InChI InChI=1S/C21H21N5O3/c27-20(7-6-15-4-2-1-3-5-15)25-11-9-17(13-25)26-14-19(23-24-26)18-12-16(21(28)29)8-10-22-18/h1-5,8,10,12,14,17H,6-7,9,11,13H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498675
(CHEMBL3621881)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)[C@@H]1CCCN(C1)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C20H19N5O3/c26-19(14-5-2-1-3-6-14)24-10-4-7-16(12-24)25-13-18(22-23-25)17-11-15(20(27)28)8-9-21-17/h1-3,5-6,8-9,11,13,16H,4,7,10,12H2,(H,27,28)/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM50498679
(CHEMBL3621879)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCCN(C1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C21H21N5O3/c27-20(11-15-5-2-1-3-6-15)25-10-4-7-17(13-25)26-14-19(23-24-26)18-12-16(21(28)29)8-9-22-18/h1-3,5-6,8-9,12,14,17H,4,7,10-11,13H2,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM50498685
(CHEMBL3621864)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCN(CC1)C(=O)CCc1ccccc1 Show InChI InChI=1S/C22H23N5O3/c28-21(7-6-16-4-2-1-3-5-16)26-12-9-18(10-13-26)27-15-20(24-25-27)19-14-17(22(29)30)8-11-23-19/h1-5,8,11,14-15,18H,6-7,9-10,12-13H2,(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4A
(Homo sapiens (Human)) | BDBM50498661
(CHEMBL3621865)Show InChI InChI=1S/C13H13N5O3/c1-8(19)17-5-10(6-17)18-7-12(15-16-18)11-4-9(13(20)21)2-3-14-11/h2-4,7,10H,5-6H2,1H3,(H,20,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4A (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498670
(CHEMBL3621866)Show InChI InChI=1S/C14H15N5O3/c1-2-13(20)18-6-10(7-18)19-8-12(16-17-19)11-5-9(14(21)22)3-4-15-11/h3-5,8,10H,2,6-7H2,1H3,(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4C
(Homo sapiens (Human)) | BDBM26113
(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)Show InChI InChI=1S/C7H5NO4/c9-6(10)4-1-2-8-5(3-4)7(11)12/h1-3H,(H,9,10)(H,11,12) | PDB
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| Article
PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4C (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498671
(CHEMBL3621875)Show InChI InChI=1S/C15H17N5O3/c1-10(21)19-6-2-3-12(8-19)20-9-14(17-18-20)13-7-11(15(22)23)4-5-16-13/h4-5,7,9,12H,2-3,6,8H2,1H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4A
(Homo sapiens (Human)) | BDBM50498662
(CHEMBL3621851)Show InChI InChI=1S/C8H6N4O2/c13-8(14)5-1-2-9-6(3-5)7-4-10-12-11-7/h1-4H,(H,13,14)(H,10,11,12) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4A (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4C
(Homo sapiens (Human)) | BDBM50498666
(CHEMBL3621850)Show SMILES ON(CCCCNCc1ccc(COC(=O)Nc2cccc3ccccc23)cc1)CC(=O)\C=C\C(O)=O Show InChI InChI=1S/C28H31N3O6/c32-24(14-15-27(33)34)19-31(36)17-4-3-16-29-18-21-10-12-22(13-11-21)20-37-28(35)30-26-9-5-7-23-6-1-2-8-25(23)26/h1-2,5-15,29,36H,3-4,16-20H2,(H,30,35)(H,33,34)/b15-14+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4C (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498685
(CHEMBL3621864)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCN(CC1)C(=O)CCc1ccccc1 Show InChI InChI=1S/C22H23N5O3/c28-21(7-6-16-4-2-1-3-5-16)26-12-9-18(10-13-26)27-15-20(24-25-27)19-14-17(22(29)30)8-11-23-19/h1-5,8,11,14-15,18H,6-7,9-10,12-13H2,(H,29,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM50498663
(CHEMBL3621882)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)[C@H]1CCCN(C1)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C20H19N5O3/c26-19(14-5-2-1-3-6-14)24-10-4-7-16(12-24)25-13-18(22-23-25)17-11-15(20(27)28)8-9-21-17/h1-3,5-6,8-9,11,13,16H,4,7,10,12H2,(H,27,28)/t16-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498678
(CHEMBL3621871)Show SMILES CCCC(=O)N1CCC(C1)n1cc(nn1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C16H19N5O3/c1-2-3-15(22)20-7-5-12(9-20)21-10-14(18-19-21)13-8-11(16(23)24)4-6-17-13/h4,6,8,10,12H,2-3,5,7,9H2,1H3,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 3A
(Homo sapiens (Human)) | BDBM50498689
(CHEMBL3621857)Show InChI InChI=1S/C16H14N4O2/c21-16(22)13-6-8-17-14(10-13)15-11-20(19-18-15)9-7-12-4-2-1-3-5-12/h1-6,8,10-11H,7,9H2,(H,21,22) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM3A (unknown origin) using H3(1-21)K9Me2-GGK-biotin substrate incubated for 5 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM50498673
(CHEMBL3621852)Show InChI InChI=1S/C11H8N2O2/c14-11(15)8-4-6-13-10(7-8)9-3-1-2-5-12-9/h1-7H,(H,14,15) | PDB
UniProtKB/SwissProt
antibodypedia
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| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM50498686
(CHEMBL3621863)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCN(CC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C21H21N5O3/c27-20(12-15-4-2-1-3-5-15)25-10-7-17(8-11-25)26-14-19(23-24-26)18-13-16(21(28)29)6-9-22-18/h1-6,9,13-14,17H,7-8,10-12H2,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498687
(CHEMBL3621862)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCN(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C20H19N5O3/c26-19(14-4-2-1-3-5-14)24-10-7-16(8-11-24)25-13-18(22-23-25)17-12-15(20(27)28)6-9-21-17/h1-6,9,12-13,16H,7-8,10-11H2,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498669
(CHEMBL3621859)Show SMILES CCOC(=O)N1CCC(CC1)n1cc(nn1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C16H19N5O4/c1-2-25-16(24)20-7-4-12(5-8-20)21-10-14(18-19-21)13-9-11(15(22)23)3-6-17-13/h3,6,9-10,12H,2,4-5,7-8H2,1H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498676
(CHEMBL3621868)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CN(C1)C(=O)c1ccccc1 Show InChI InChI=1S/C18H15N5O3/c24-17(12-4-2-1-3-5-12)22-9-14(10-22)23-11-16(20-21-23)15-8-13(18(25)26)6-7-19-15/h1-8,11,14H,9-10H2,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498682
(CHEMBL3621876)Show SMILES CCC(=O)N1CCCC(C1)n1cc(nn1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C16H19N5O3/c1-2-15(22)20-7-3-4-12(9-20)21-10-14(18-19-21)13-8-11(16(23)24)5-6-17-13/h5-6,8,10,12H,2-4,7,9H2,1H3,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498686
(CHEMBL3621863)Show SMILES OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCN(CC1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C21H21N5O3/c27-20(12-15-4-2-1-3-5-15)25-10-7-17(8-11-25)26-14-19(23-24-26)18-13-16(21(28)29)6-9-22-18/h1-6,9,13-14,17H,7-8,10-12H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 2A
(Homo sapiens (Human)) | BDBM26113
(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)Show InChI InChI=1S/C7H5NO4/c9-6(10)4-1-2-8-5(3-4)7(11)12/h1-3H,(H,9,10)(H,11,12) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM2A (unknown origin) |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498677
(CHEMBL3621877)Show SMILES CCCC(=O)N1CCCC(C1)n1cc(nn1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C17H21N5O3/c1-2-4-16(23)21-8-3-5-13(10-21)22-11-15(19-20-22)14-9-12(17(24)25)6-7-18-14/h6-7,9,11,13H,2-5,8,10H2,1H3,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 5C
(Homo sapiens (Human)) | BDBM50498668
(CHEMBL3621860)Show SMILES CCC(=O)N1CCC(CC1)n1cc(nn1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C16H19N5O3/c1-2-15(22)20-7-4-12(5-8-20)21-10-14(18-19-21)13-9-11(16(23)24)3-6-17-13/h3,6,9-10,12H,2,4-5,7-8H2,1H3,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM5C (unknown origin) using H3(1-21)K4Me3-GGK-biotin substrate incubated for 20 mins by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
Lysine-specific demethylase 4A
(Homo sapiens (Human)) | BDBM50498670
(CHEMBL3621866)Show InChI InChI=1S/C14H15N5O3/c1-2-13(20)18-6-10(7-18)19-8-12(16-17-19)11-5-9(14(21)22)3-4-15-11/h3-5,8,10H,2,6-7H2,1H3,(H,21,22) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of KDM4A (unknown origin) using H3(1-21)K9Me3-GGK-biotin substrate by alpha screen assay |
Medchemcomm 5: 1879-1886 (2014)
Article DOI: 10.1039/C4MD00291A
BindingDB Entry DOI: 10.7270/Q2KH0RBN |
More data for this
Ligand-Target Pair | |
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