Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM26113 (2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of KDM2A (unknown origin) | Medchemcomm 5: 1879-1886 (2014) Article DOI: 10.1039/C4MD00291A BindingDB Entry DOI: 10.7270/Q2KH0RBN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM26113 (2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of KDM2A (unknown origin) | J Med Chem 56: 7222-31 (2013) Article DOI: 10.1021/jm400624b BindingDB Entry DOI: 10.7270/Q2SB475V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM26113 (2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM26113 (2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Oxford | Assay Description The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was... | Nat Chem Biol 12: 539-45 (2016) Article DOI: 10.1038/nchembio.2087 BindingDB Entry DOI: 10.7270/Q27P8X6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM26113 (2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of KDM2A (unknown origin) expressed in Escherichia coli using Biotin H3 (28 to 48 residues) Me2 KDM2A Cognate Ligande/10 uM alpha-ketoglut... | J Med Chem 59: 1580-98 (2016) Article DOI: 10.1021/acs.jmedchem.5b01527 BindingDB Entry DOI: 10.7270/Q2P84DRX | |||||||||||
More data for this Ligand-Target Pair |