BDBM50498694 CHEMBL3621872
SMILES: OC(=O)c1ccnc(c1)-c1cn(nn1)C1CCN(C1)C(=O)c1ccccc1
InChI Key: InChIKey=QAMWHKMCPLOTNR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Homo sapiens lysine demethylase 2A (KDM2A) (Homo sapiens (Human)) | BDBM50498694 (CHEMBL3621872) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of KDM2A (unknown origin) using Biotin-H3(28-48)K36Me2 and H3(28-48)K36Me2 substrates incubated for 30 mins by alpha screen assay | Medchemcomm 5: 1879-1886 (2014) Article DOI: 10.1039/c4md00291a BindingDB Entry DOI: 10.7270/Q2KH0RBN | |||||||||||
More data for this Ligand-Target Pair |