26 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28324649	99	Sulfonamides as Selective Na	Amgen
28287723	73	Sulfonamides as Selective Na	Amgen
27994738	50	Sulfonamides as Selective Na	Amgen
26985315	49	Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models.	Xenon Pharmaceuticals
26890998	572	Single Residue Substitutions That Confer Voltage-Gated Sodium Ion Channel Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx-1.	Amgen
25927480	36	Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications.	Merck Research Laboratories
25658507	218	Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel.	Amgen
24601592	48	Imidazol-1-ylethylindazole voltage-gated sodium channel ligands are neuroprotective during optic neuritis in a mouse model of multiple sclerosis.	University College London
23121096	86	Ion channels as therapeutic targets: a drug discovery perspective.	Pfizer
19027197	44	2D- and 3D-QSAR of tocainide and mexiletine analogues acting as Na(v)1.4 channel blockers.	Universit£
14998340	15	3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers.	Purdue Pharma
21634377	73	Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain.	Amgen
12773053	2	Design, synthesis, and evaluation of analogues of 3,3,3-trifluoro-2-hydroxy-2-phenyl-propionamide as orally available general anesthetics.	University of Virginia
27441383	117	Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors.	Amgen
30943032	31	Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Na	Genentech
30576602	157	Discovery of Indole- and Indazole-acylsulfonamides as Potent and Selective Na	Bristol-Myers Squibb Research and Development
30538065	48	The discovery and optimization of benzimidazoles as selective Na	Pfizer
31012583	128	Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform Na	Siteone Therapeutics
24440379	179	Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators.	University of Ljubljana
24148992	60	Novel state-dependent voltage-gated sodium channel modulators, based on marine alkaloids from Agelas sponges.	University of Ljubljana
29037948	70	Discovery of aminocyclohexene analogues as selective and orally bioavailable hNav1.7 inhibitors for analgesia.	Wuxi Apptec (Shanghai)
29029933	45	Highly potent and selective Na	Pfizer
30346167	71	Discovery of Tarantula Venom-Derived Na	Amgen
28682065	133	Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of Na	Icagen
7932531	55	Inhibitors of HIV-1 proteinase containing 2-heterosubstituted 4-amino-3-hydroxy-5-phenylpentanoic acid: synthesis, enzyme inhibition, and antiviral activity.	Sandoz Forschungsinstitut Ges.M.B.H.