The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27541007 |
45 |
Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors. |
University of Ljubljana |
27096044 |
30 |
Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design. |
Cubist Pharmaceuticals |
26786695 |
12 |
Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB. |
Cubist Pharmaceuticals |
26487916 |
8 |
Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors. |
Cubist Pharmaceuticals |
25137573 |
7 |
Pyridine-3-carboxamide-6-yl-ureas as novel inhibitors of bacterial DNA gyrase: structure based design, synthesis, SAR and antimicrobial activity. |
University of Leeds |
24959892 |
152 |
Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099). |
Astrazeneca |
24629449 |
2 |
Computer-aided identification of novel 3,5-substituted rhodanine derivatives with activity against Staphylococcus aureus DNA gyrase. |
University of The Sciences |
24098982 |
39 |
Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents. |
Astrazeneca R&D Boston |
24900376 |
5 |
Combatting Drug-Resistant Bacteria with Gyrase and Topoisomerase IV Inhibitors: Patent Highlight. |
TBA |
22814212 |
10 |
Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV. |
Astrazeneca |
22041057 |
14 |
Pyrrolamide DNA gyrase inhibitors: optimization of antibacterial activity and efficacy. |
Astrazeneca R&D Boston |
26460684 |
39 |
Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors. |
Cubist Pharmaceuticals |
25288496 |
106 |
Structure-guided design and development of novel benzimidazole class of compounds targeting DNA gyraseB enzyme of Staphylococcus aureus. |
Birla Institute of Technology & Science-Pilani |
29778894 |
30 |
New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity. |
University of Ljubljana |
29751233 |
2 |
New developments in non-quinolone-based antibiotics for the inhibiton of bacterial gyrase and topoisomerase IV. |
Islamia College University |
27689732 |
30 |
Linker-switch approach towards new ATP binding site inhibitors of DNA gyrase B. |
University of Ljubljana |