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20 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
24035338 82 Discovery of 2,8-diazaspiro[4.5]decane-based trisubstituted urea derivatives as highly potent soluble epoxide hydrolase inhibitors and orally active drug candidates for treating hypertension.EBI Toray Industries
21354674 14 The many faces of the adamantyl group in drug design.EBI University of Sydney
19645482 245 Discovery of a highly potent, selective, and bioavailable soluble epoxide hydrolase inhibitor with excellent ex vivo target engagement.EBI Merck Research Laboratories
17616115 61 Orally bioavailable potent soluble epoxide hydrolase inhibitors.EBI University of California Davis
21211973 35 1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.EBI Ar£Te Therapeutics
20812725 103 1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain.EBI Department of Entomology and University of California Davis Cancer Center
17046265 66 Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase.EBI Department of Entomology and University of California Davis Cancer Center
16908134 98 Peptidyl-urea based inhibitors of soluble epoxide hydrolases.EBI University of California
15887969 64 Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility.EBI Department of Entomology and University of California Davis Cancer Center
15056008 72 Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility.EBI University of California Davis
12620084 17 QSAR and classification of murine and human soluble epoxide hydrolase inhibition by urea-like compounds.EBI The Pennsylvania State University
31436984 54 Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.EBI Goethe-University Frankfurt
31488357 19 Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors.EBI Universitat De Barcelona
8423594 39 Development of selective tight-binding inhibitors of leukotriene A4 hydrolase.EBI Scripps Research Institute
29366648 98 Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase.EBI University of California Davis
29803731 68 Adamantyl thioureas as soluble epoxide hydrolase inhibitors.EBI University of California Davis