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8 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27997879 15 Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase.EBI Harvard Medical School
21726077 51 The lipogenesis pathway as a cancer target.EBI Wayne State University
1479587 4 ATP-citrate lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-beta-lactam containing analogues of citric acid as potential tight-binding inhibitors.EBI Smithkline Beecham Pharmaceuticals
9733484 39 ATP-Citrate lyase as a target for hypolipidemic intervention. 2. Synthesis and evaluation of (3R,5S)-omega-substituted-3-carboxy-3, 5-dihydroxyalkanoic acids and their gamma-lactone prodrugs as inhibitors of the enzyme in vitro and in vivo.EBI Smithkline Beecham Pharmaceuticals
8784456 55 ATP-citrate lyase as a target for hypolipidemic intervention. Design and synthesis of 2-substituted butanedioic acids as novel, potent inhibitors of the enzyme.EBI Smithkline Beecham Pharmaceuticals
7853346 13 Synthesis of novel thiol-containing citric acid analogues. Kinetic evaluation of these and other potential active-site-directed and mechanism-based inhibitors of ATP citrate lyase.EBI Smithkline Beecham Pharmaceuticals
30195238 26 ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism.EBI University of Pisa
2788743 6 Synthesis and hypolipidemic and antidiabetogenic activities of beta,beta,beta',beta'-tetrasubstituted, long-chain dioic acids.EBI Hebrew University