The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28075591 |
16 |
Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A. |
Selcia |
| 27815116 |
1 |
Thioxylated cyclosporin A for studying protein-drug interactions. |
Technical University Dresden |
| 27687672 |
14 |
Design and synthesis of peptide-based macrocyclic cyclophilin inhibitors. |
Astrazeneca |
| 24831536 |
2 |
From chemical tools to clinical medicines: nonimmunosuppressive cyclophilin inhibitors derived from the cyclosporin and sanglifehrin scaffolds. |
Novartis Institutes For Biomedical Research |
| 25310383 |
50 |
Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition. |
Novartis Institutes For Biomedical Research |
| 23964991 |
11 |
Anti-inflammatory effects of extracellular cyclosporins are exclusively mediated by CD147. |
Max Planck Research Unit For Enzymology of Protein Folding |
| 24900335 |
6 |
Ranking high affinity ligands of low solubility by NMR spectroscopy. |
TBA |
| 21396746 |
4 |
Discovery of a potent peptidic cyclophilin A inhibitor Trp-Gly-Pro. |
Fudan University |
| 20943390 |
40 |
Synthesis and biological evaluation of [D-lysine]8cyclosporin A analogs as potential anti-HCV agents. |
Scynexis |
| 18571405 |
2 |
Simultaneous identification of multiple receptors of natural product using an optimized cDNA phage display cloning. |
Chinese Academy of Sciences |
| 15357990 |
6 |
Synthesis and neurotrophic activity of nonimmunosuppressant cyclosporin A derivatives. |
Guilford Pharmaceuticals |
| 11472213 |
12 |
Structure-activity studies of ground- and transition-state analogue inhibitors of cyclophilin. |
Southern Methodist University |
| 10794694 |
32 |
Design of a Gag pentapeptide analogue that binds human cyclophilin A more efficiently than the entire capsid protein: new insights for the development of novel anti-HIV-1 drugs. |
Departement D'Ingenierie Et D'Etudes Des Proteines |
| 14643337 |
38 |
Synthesis of non-immunosuppressive cyclophilin-Binding cyclosporin A derivatives as potential anti-HIV-1 drugs. |
Centre De Recherche De Paris |
| 21963115 |
3 |
Oligopeptide cyclophilin inhibitors: a reassessment. |
Max Planck Research Unit For Enzymology of Protein Folding |
| 18212100 |
3 |
Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent. |
Southern Research Institute |
| 24900244 |
8 |
Facile synthesis of a fluorescent cyclosporin a analogue to study cyclophilin 40 and cyclophilin 18 ligands. |
TBA |
| 19933795 |
12 |
SCY-635, a novel nonimmunosuppressive analog of cyclosporine that exhibits potent inhibition of hepatitis C virus RNA replication in vitro. |
Scynexis |
| 19734911 |
20 |
Augmented photoswitching modulates immune signaling. |
Max Planck Research Unit For Enzymology of Protein Folding |
| 19691347 |
24 |
Discovering potent small molecule inhibitors of cyclophilin A using de novo drug design approach. |
East China University of Science and Technology |
| 19328002 |
44 |
Discovery of dual inhibitors targeting both HIV-1 capsid and human cyclophilin A to inhibit the assembly and uncoating of the viral capsid. |
Peking University |
| 16451056 |
23 |
Structure-based design, synthesis, and biological evaluation of novel inhibitors of human cyclophilin A. |
University of Montpellier |
| 12431052 |
22 |
Molecular docking and 3D-QSAR studies on gag peptide analogue inhibitors interacting with human cyclophilin A. |
Chinese Academy of Sciences |
| 31188592 |
39 |
Why Some Targets Benefit from beyond Rule of Five Drugs. |
Boston University |
| 26613291 |
11 |
Structure-Based Discovery of Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections. |
Chonnam National University |
| 26564266 |
22 |
Identification, synthesis and pharmacological evaluation of novel anti-EV71 agents via cyclophilin A inhibition. |
East China University of Science and Technology |
| 7966126 |
3 |
Improved binding affinity for cyclophilin A by a cyclosporin derivative singly modified at its effector domain. |
Sandoz Pharma |
| 7650689 |
12 |
The role of water molecules in the structure-based design of (5-hydroxynorvaline)-2-cyclosporin: synthesis, biological activity, and crystallographic analysis with cyclophilin A. |
Sandoz Pharma |
| 30074795 |
24 |
Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle. |
Gilead Sciences |
| 27539124 |
1 |
Characterization of MymA protein as a flavin-containing monooxygenase and as a target of isoniazid. |
Miranda House |
| 17097290 |
29 |
Benzothiazole benzimidazole (S)-isothiazolidinone derivatives as protein tyrosine phosphatase-1B inhibitors. |
Incyte |
Search and Browse
