The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 25927480 |
36 |
Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications. |
Merck Research Laboratories |
| 25026046 |
42 |
Studies examining the relationship between the chemical structure of protoxin II and its activity on voltage gated sodium channels. |
Purdue Pharma |
| 19388676 |
21 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies. |
Johnson & Johnson Pharmaceutical Research & Development |
| 9703475 |
19 |
Synthesis and pharmacological evaluation of N,N'-diarylguanidines as potent sodium channel blockers and anticonvulsant agents. |
Cambridge Neuroscience |
| 9685245 |
22 |
Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels. |
Cambridge Neuroscience |
| 8295214 |
21 |
Synthesis and pharmacological evaluation of phenylacetamides as sodium-channel blockers. |
Warner-Lambert |
| 21962108 |
14 |
Lactam-stabilized helical analogues of the analgesicµ-conotoxin KIIIA. |
Monash University |
| 18640044 |
24 |
Discovery and stereoselective synthesis of the novel isochroman neurokinin-1 receptor antagonist 'CJ-17,493'. |
Pfizer |
| 17724025 |
8 |
Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels. |
University of Utah |
| 8691482 |
25 |
A structure-activity relationship study of novel phenylacetamides which are sodium channel blockers. |
Warner-Lambert |
| 23910595 |
3 |
Synthesis and evaluation of a 125I-labeled iminodihydroquinoline-derived tracer for imaging of voltage-gated sodium channels. |
Institute of Nuclear Medicine |
| 23707919 |
7 |
Expanding chemical diversity of conotoxins: peptoid-peptide chimeras of the sodium channel blocker ?-KIIIA and its selenopeptide analogues. |
University of Gdansk |
| 29116786 |
265 |
Discovery of a Potent, Selective T-type Calcium Channel Blocker as a Drug Candidate for the Treatment of Generalized Epilepsies. |
Idorsia Pharmaceuticals |
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