Affinity Data by PubMed id=9703475

PubMed code 9703475

Found 19 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066417 (CHEMBL112806 \| N-(4-Benzyloxy-phenyl)-N'-(4-tert-b...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066427 (CHEMBL109210 \| N,N'-Bis-(4-butyl-phenyl)-guanidine) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066420 (CHEMBL112132 \| N-(4-Benzyloxy-phenyl)-N'-(4-butyl-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066423 (CHEMBL326502 \| N,N'-Bis-(4-butoxy-phenyl)-guanidin...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066425 (CHEMBL112515 \| N,N'-Bis-(4-phenoxy-phenyl)-guanidi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50010754 (CHEMBL81626 \| N,N'-Bis-(4-isopropyl-phenyl)-guanid...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066428 (CHEMBL326774 \| N-Acenaphthen-5-yl-N'-(4-sec-butyl-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066057 (CHEMBL110909 \| CHEMBL320199 \| N,N'-Bis-(4-sec-buty...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066419 (CHEMBL326741 \| N,N'-Bis-(4-hexyl-phenyl)-guanidine) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066424 (CHEMBL331126 \| N,N'-Bis-(4-phenylsulfanyl-phenyl)-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066422 (CHEMBL326130 \| N,N'-Bis-biphenyl-4-yl-guanidine) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50010736 (CHEMBL78083 \| N,N'-Bis-(4-ethyl-phenyl)-guanidine) Show SMILES CCc1ccc(NC(N)=Nc2ccc(CC)cc2)cc1 \|w:9.9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066421 (CHEMBL320340 \| N,N'-Bis-(4-tert-butyl-phenyl)-guan...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066068 (CHEMBL28853 \| N-Acenaphthen-5-yl-N'-(4-methoxy-nap...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066429 (CHEMBL325215 \| N-(4-Butoxy-phenyl)-N'-[4-(4-hydrox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066430 (2-(4-Methyl-piperazin-1-yl)-5-(2,3,5-trichloro-phe...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM30705 (CHEMBL744 \| MLS000069369 \| RILUZOLE \| SMR000058231...) Show SMILES Nc1nc2ccc(OC(F)(F)F)cc2s1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50066426 (CHEMBL114716 \| N,N'-Bis-[4-(4-hydroxy-butyl)-pheny...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rattus norvegicus)	BDBM50010743 (N,N'-Di-p-tolyl-guanidine) Show SMILES Cc1ccc(NC(N)=Nc2ccc(C)cc2)cc1 \|w:8.8\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brain				J Med Chem 41: 3298-302 (1998) Article DOI: 10.1021/jm980134b BindingDB Entry DOI: 10.7270/Q2Q52Q8W
Cambridge NeuroScience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%